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METHYL CINNAMATE.

Avoid CAS 103-26-4 / PERFUMING

Methyl Cinnamate is an organic ester and a derivative of cinnamic acid, primarily recognized for its aromatic profile. In skincare, it has been investigated for potential antioxidant, anti-inflammatory, antimicrobial, and antimelanogenic properties, which may support skin health and barrier function.

Fragrance Antioxidant Anti-inflammatory Antimicrobial Antimelanogenic

Science

As a cinnamic acid derivative, Methyl Cinnamate operates by neutralizing reactive oxygen species, thereby mitigating oxidative stress that can compromise skin barrier integrity. It also demonstrates anti-inflammatory properties to help modulate inflammatory responses and antimelanogenic effects to regulate melanin production.


Research

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Cinnamic Acid Derivatives as Potential Multifunctional Agents in Cosmetic Formulations Used for Supporting the Treatment of Selected Dermatoses (NIH)

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Methyl Cinnamate exhibits good solubility in organic solvents and most non-volatile oils, including ethanol, ether, glycerin, propylene glycol, mineral oil, benzene, olive oil, and paraffin. It is insoluble or only slightly soluble in water. It is recommended to add it at the last stage of formulation and avoid temperatures exceeding 40°C. Generally, it is non-discoloring in most media.


Safety

CIR Status
Not reviewed
Max tested
0.31%
Sensitization risk High

Methyl Cinnamate is listed by the FDA as a synthetic flavoring substance permitted in food. However, no explicit CIR or SCCS safety assessment specifically for its use in skincare is available. It is classified as a skin sensitizer (Category 1, H317) with the potential to cause allergic skin reactions. IFRA guidelines suggest a maximum skin exposure level of 0.31% for fine fragrances.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Avoid

Despite demonstrating potential antioxidant and anti-inflammatory benefits, Methyl Cinnamate is classified as a skin sensitizer and primarily functions as a fragrance, rendering it generally unsuitable for precision skincare formulations.


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