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METHYL AMYL KETONE.

Avoid CAS 110-43-0 / PERFUMING

Methyl Amyl Ketone is an organic compound primarily recognized for its capabilities as a solvent and its aromatic contribution as a fragrance ingredient. It can be readily absorbed into the skin.

solvent fragrance

Science

As a primary solvent, Methyl Amyl Ketone facilitates the dissolution of other substances within formulations. Its inherent volatile scent allows for its inclusion as a fragrance component. Evidence suggests it can be absorbed through the skin following topical exposure.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Methyl Amyl Ketone typically exhibits stability under ambient conditions; however, prolonged atmospheric exposure can initiate a slow decomposition process. This decomposition leads to the formation of peroxides, which subsequently increase the risk of fire or explosion. Elevated temperatures accelerate this peroxidative reaction.

Conflicts

  • strong oxidizing agents
  • some acids
  • some bases
  • amines
  • some forms of plastic

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

Methyl Amyl Ketone is identified as an irritant to ocular tissues, skin, and the respiratory tract. Exposure may manifest as irritation of the skin and eyes, respiratory discomfort, headaches, vomiting, and nausea. Chronic dermal exposure can result in persistent skin irritation, characterized by cracking and dryness. It has not been classified as a human carcinogen by authoritative bodies such as the TCEQ, US EPA, National Toxicology Program, or International Agency for Research on Cancer. A specific safety assessment by the Cosmetic Ingredient Review (CIR) or Scientific Committee on Consumer Safety (SCCS) for Methyl Amyl Ketone (Heptan-2-one) is not available; existing CIR reports pertain to Methyl Isobutyl Ketone (MIBK), a distinct compound.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Avoid

Methyl Amyl Ketone functions as a solvent and fragrance but is associated with notable skin, eye, and respiratory irritation risks. The absence of specific safety assessments for its use in cosmetic formulations by key regulatory bodies, coupled with its irritant profile, renders it unsuitable for precision skincare products.


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