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METHACRYLOYLETHYL PHOSPHATE.

Insufficient Data CAS 52628-03-2 / NAIL CONDITIONING

Methacryloylethyl Phosphate is a hydrophilic monomer and bifunctional crosslinker. It functions in formulations as a surfactant and lubricant, and when polymerized into related compounds, it demonstrates potential to support the skin's stratum corneum barrier by maintaining structural integrity.

Surfactant Lubricant Adhesion/Cohesion Promoter

Science

As a hydrophilic monomer, Methacryloylethyl Phosphate acts as a lubricating agent and surfactant. In its polymerized form, specifically compounds like poly[2-methacryloyloxyethyl phosphorylcholine], it has been observed to protect the skin's stratum corneum barrier. This protective action involves preventing the disruption of the inter-lamellar bilayer structure that can be caused by extensive hydration, thereby supporting barrier function.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This hydrophilic monomer is prone to spontaneous polymerization when exposed to acids. To ensure its stability in formulations, it is typically supplied with polymerization inhibitors, such as 700-1000 ppm monomethyl ether hydroquinone.

Conflicts

  • Acids (causes spontaneous polymerization)

Safety

CIR Status
Safe with restrictions
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel assessed Methacryloylethyl Phosphate as part of a group of alkyl phosphates, concluding they are safe for cosmetic use when formulated to be non-irritating. However, the raw substance is classified as causing skin irritation (H315) and serious eye irritation (H319), with potential for respiratory irritation (H335). No specific maximum cosmetic concentration was identified by CIR. Neither the SCCS nor the FDA has issued a specific opinion on this ingredient.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Insufficient Data

While polymerized forms show theoretical promise for skin barrier support, direct clinical efficacy data for Methacryloylethyl Phosphate in skincare is limited, and the raw material is classified as an irritant requiring careful formulation.


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