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MELAMINE.

Avoid CAS 108-78-1 / NOT REPORTED

Melamine is an organic compound primarily utilized in industrial applications for the production of plastics and resins. It is not recognized for any beneficial properties in topical skincare, and its direct application is strongly discouraged.

Science

Melamine functions as a primary skin irritant upon direct contact. Exposure can lead to immediate irritation, and persistent or repeated contact with unprotected skin is associated with the development of dermatitis or the exacerbation of pre-existing dermatological conditions.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Melamine functions as a weak base, forming a slightly alkaline solution with an approximate pH of 7 when dissolved in water. In biological culture media, the pH of melamine aqueous solutions typically ranges between 7.5 and 9.5, influenced by concentration and temperature.

Conflicts

  • strong oxidizing agents
  • strong acids
  • isocyanates
  • halogenated organics
  • peroxides
  • phenols (acidic)
  • epoxides
  • anhydrides
  • acid halides

Safety

CIR Status
Not reviewed
Sensitization risk High

Melamine is explicitly identified as an irritant to both skin and eyes. Prolonged or repeated dermal exposure carries a risk of inducing dermatitis or worsening existing skin disorders. While severe health implications such as reproductive damage, kidney stones, and bladder cancer are primarily linked to ingestion, its significant topical irritancy renders it unsuitable for cosmetic applications.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Melamine is a documented skin irritant lacking any beneficial skincare functions, posing a high risk for adverse reactions upon topical application, and should therefore be avoided in cosmetic formulations.


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References