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MEK.

Avoid CAS 78-93-3 / PERFUMING, SOLVENT

Methyl Ethyl Ketone (MEK) is a volatile organic compound primarily recognized for its potent solvent properties in industrial applications. While occasionally appearing as a solvent or fragrance component in cosmetic formulations, it offers no direct skincare benefits.

Solvent Fragrance

Science

MEK functions primarily as a powerful solvent in formulations, effectively dissolving other substances and enhancing product scent or perfuming the skin. It acts as a strong degreaser, but research indicates no positive mechanism of action for specific skincare advantages on the skin.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

MEK is a solvent and not considered an active ingredient subject to dusting analysis.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

MEK is a volatile liquid. Its strong industrial solvent nature suggests potential instability and incompatibility within complex cosmetic formulations, particularly with sensitive active ingredients. No specific optimal pH range for its stability in skincare is reported.

Conflicts

  • Likely incompatible with many sensitive cosmetic ingredients due to its strong solvent and defatting properties.
  • Flammable liquids.

Safety

CIR Status
Not reviewed
Sensitization risk High

MEK has not been specifically reviewed by the Cosmetic Ingredient Review (CIR) Expert Panel for its safety in topical skincare. While listed in cosmetic databases for fragrance and solvent roles, available information emphasizes its industrial hazards over skincare safety. The Scientific Committee on Consumer Safety (SCCS) mentions MEK as a vehicle for testing fragrance allergens, not as a directly assessed skincare ingredient. Acute human exposure can lead to irritation of the eyes, nose, and throat, and dermatitis has been documented following dermal exposure.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to its high irritancy, lack of skincare benefits, and significant safety concerns as a strong industrial solvent, MEK is not recommended for precision skincare formulations.


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