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MAGNESIUM GLUCONATE.

Valuable CAS 3632-91-5 / SKIN CONDITIONING

Magnesium Gluconate is a mineral salt functioning as a skin-conditioning agent that significantly improves skin texture, promoting smoothness and reducing dryness. It enhances the skin's mineral balance and barrier health, contributing to revitalized and soothed skin.

Summary

Skin-conditioning Humectant Soothing Revitalizing

Science

Mechanism of Action

This ingredient works by boosting skin conditioning, leading to increased smoothness and a reduction in flakiness and roughness. It provides bioavailable magnesium to improve barrier function and possesses light humectant properties from its gluconic acid salt, aiding in skin hydration. Magnesium salts are broadly known to enhance dermal permeability and support epidermal regeneration. When combined with minerals like Zinc and Copper, Magnesium Gluconate can act as a radical scavenger, protecting cells and increasing cellular oxygenation and metabolism.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 7.8
0 7 14

Stability

Magnesium Gluconate is highly soluble in water, with slight solubility in ethanol and very minimal in methylene chloride. It is generally stable under typical storage conditions when shielded from moisture, light, and heat, but may degrade upon exposure to high temperatures or acidic environments. Its hygroscopic nature necessitates dry storage to prevent clumping.

Synergies

  • Zinc
  • Copper

Conflicts

  • strong oxidizing agents
  • bases
  • amines
  • reducing agents
  • acids
  • acid anhydrides
  • Electrolyte-sensitive gel makers / cream makers / thickeners

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not formally assessed Magnesium Gluconate; however, its gluconic acid component has been reviewed and deemed safe. The FDA lists Magnesium Gluconate as Generally Recognized As Safe (GRAS) for direct food use without specific limitations beyond good manufacturing practices. EWG indicates low concerns across categories including cancer, allergies & immunotoxicity, and developmental/reproductive toxicity.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Magnesium Gluconate is a valuable ingredient, effectively enhancing skin hydration, barrier integrity, and overall smoothness with a very low risk of irritation, making it suitable for diverse skin types and product applications.

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