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Moumoujus

M-AMINOPHENOL.

Avoid CAS 591-27-5 / HAIR DYEING

M-Aminophenol functions as an oxidative hair dye precursor, integral to formulations that impart permanent color to hair. Its primary role involves chemical reactions within the hair shaft, producing colorants for hair pigmentation. This ingredient is not intended for direct skincare application.

Summary

hair dyeing

Science

Mechanism of Action

M-Aminophenol does not exhibit a mechanism of action on the skin. Its function is exclusively within hair dyeing, where it chemically reacts with hydrogen peroxide to form color molecules inside the hair shaft, thereby changing the hair's pigment.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

M-Aminophenol is not typically encountered or 'dusted' in precision skincare formulations, as its application is strictly limited to hair dyeing.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

M-Aminophenol degrades under exposure to air and light. Solutions demonstrate short-term stability, maintaining integrity for up to 6 hours at room temperature when stored under an inert atmosphere and protected from light. Higher concentrations (200 mg/ml) can achieve stability for up to 9 days at 4°C under similar protective conditions. In oxidative hair dyes, it is mixed with hydrogen peroxide immediately prior to use, with the resulting color being dependent on the dyeing solution's pH.

Conflicts

  • strong oxidizing agents (before intended use in hair dyes)
  • air
  • light

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
2%
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel deemed Aminophenols safe for use as hair dyes. The Scientific Committee on Cosmetic Products and Non-Food Products (SCCNFP) advises safe use in permanent hair dye formulations up to a maximum concentration of 2.0%. However, when combined with hydrogen peroxide for application, the maximum in-use concentration must not exceed 1.0%. Cosmetic products containing this substance are required to carry a label warning regarding a risk of sensitization. It is regulated in the EU under the Cosmetics Directive, Annex III, Part 2, and EWG classifies it with high use restrictions. The FDA regulates colorants in cosmetics in the United States.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

M-Aminophenol is an ingredient exclusively used for hair dyeing, offering no identified benefits for skin, and its high irritancy and sensitization potential deem it unsuitable for precision skincare formulations.

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