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LIVER EXTRACT.

Insufficient Data CAS 8002-47-9 / SKIN CONDITIONING

Liver Extract is a nutrient-dense biological derivative containing essential vitamins such as B12 and A, alongside folic acid and iron. It is theorized to contribute to overall dermal health by supporting cellular differentiation and the body's intrinsic detoxification mechanisms, potentially fostering clearer, less irritated skin.

skin conditioning pore clearing anti-inflammatory cell differentiation promotion

Science

This extract supplies Vitamin A, which is crucial for the healthy differentiation of skin cells and the endogenous production of steroids. It concurrently bolsters the skin's innate resistance to infection and inflammation. Furthermore, its nutritional components are believed to indirectly support hepatic function, which is integral for detoxification, hormone metabolism, and nutrient absorption, thereby contributing to clearer skin and reduced pore impactions.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 6.5 – 7.5
0 7 14

Stability

A 2% solution of Liver Extract naturally exhibits a pH of approximately 7.0 ± 0.5, indicating optimal stability within the range of 6.5-7.5. However, general skincare formulations typically require a pH between 4.5-6.5 to maintain product stability and skin barrier integrity. If the extract contains sensitive biomolecules like peptides, strong acids or potent antioxidants should be used with caution as they may induce destabilization. Rigorous sourcing and manufacturing are essential to mitigate the potential for heavy metal contamination inherent in natural extracts.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel and the Scientific Committee on Consumer Safety (SCCS) have not published specific safety assessments for Liver Extract as a cosmetic ingredient. In the U.S., cosmetic products and ingredients (excluding color additives) do not require pre-market FDA approval, and Liver Extract is not listed among FDA's prohibited or restricted cosmetic ingredients.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While Liver Extract presents a theoretical benefit profile through its rich vitamin and mineral content, the absence of dedicated cosmetic safety assessments, clinical efficacy data, and specific irritancy/comedogenicity information necessitates further research before recommending its widespread inclusion in precision skincare formulations.


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