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Moumoujus

LIPPIA CITRIODORA LEAF EXTRACT.

Questionable CAS - / ASTRINGENT, PERFUMING

Lippia Citriodora Leaf Extract, derived from the lemon verbena plant, is a botanical ingredient rich in beneficial compounds, offering antioxidant, anti-inflammatory, and antimicrobial properties. It is mechanistically understood to influence sebum regulation, soothe skin irritation, and contribute to a refined pore appearance.

Summary

Antioxidant Anti-inflammatory Antimicrobial Skin Conditioning Sebum Regulating Astringent Soothing Perfuming

Science

Mechanism of Action

This extract's efficacy stems from its complex phytochemical profile, particularly phenolic and flavonoid compounds like verbascoside, which act as potent antioxidants, safeguarding skin against oxidative damage and preventing squalene oxidation. Its anti-inflammatory and antimicrobial actions, combined with monoterpenic alcohols, help alleviate redness and irritation. Furthermore, the extract is believed to reduce sebocyte differentiation markers, thereby decreasing lipid accumulation and sebum secretion, which aids in tightening skin pores.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

As a natural botanical extract known for specific bioactivities, Lippia Citriodora Leaf Extract is not typically considered an ingredient used for cosmetic 'dusting'.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

A hydroglycerin extract is typically obtained by maceration, a cold process designed to preserve heat-sensitive phytochemicals present in the plant material.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

Lippia Citriodora Leaf Extract is classified as an allergen and is regulated in regions such as Europe and the United Kingdom. The essential oil of Lippia citriodora is specifically prohibited for use as a fragrance ingredient due to documented sensitization and phototoxicity concerns. There is insufficient information from CIR or SCCS regarding a maximum safe concentration for topical use. Some studies indicate potential genotoxic effects of its essential oil at high concentrations, specifically from components like citral. An aqueous extract was well tolerated in animal studies at doses up to 200 mg/kg via daily IP injection for 21 days.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Despite promising mechanistic data suggesting benefits for oily and sensitive skin, the absence of direct topical clinical studies for Lippia Citriodora Leaf Extract, combined with its classification as an allergen and unreviewed CIR status, renders its inclusion questionable for a precision skincare formulation.

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