Science
Mechanism of Action
This extract combats free radicals, thereby providing antioxidant protection against oxidative damage. Its anti-inflammatory capabilities help to calm redness and reduce irritation, while its antimicrobial action contributes to maintaining skin purity. As a skin conditioning and astringent agent, it aids in refining skin texture, clarifying the complexion, and may support detoxification by removing excess oils and impurities.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 In vitro studies have indicated potential skin brightening properties for a related verbena essence.
- 02 An aqueous extract of Lippia citriodora leaves demonstrated low cytotoxicity in vitro, showing cell viability greater than the IC50 value in HepG2 cells at concentrations up to 200 µg/mL.
Transparency
Dusting Analysis
The Formula
Formulation
Conflicts
- Exposure to direct sunlight or UV radiation after application, due to potential phototoxicity stemming from its essential oil components.
- Use as a fragrance ingredient in cosmetic formulations, as it carries a high risk of sensitization and is prohibited by EU regulations for this purpose.
Safety
Safety Profile
The EU Cosmetics Regulation 1223/2009 recommends 'PROHIBITED' status for 'LIPPIA CITRIODORA LEAF/FLOWER OIL' when used as a fragrance ingredient due to established sensitization and phototoxicity risks. EWG Skin Deep classifies related extracts as 'Unacceptable' for EWG VERIFIED products, citing 'HIGH Allergies & Immunotoxicity' and 'HIGH Use Restrictions,' explicitly stating it is 'Banned or found unsafe for use in cosmetics' by the European Union. It is recognized as an EU Allergen and has the potential to cause irritation, particularly for individuals with sensitive skin. While its oil form was historically listed by the FDA for food use, it is 'no longer FEMA GRAS™'.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite potential antioxidant and conditioning benefits, the significant risks of sensitization, phototoxicity, and general irritation, coupled with its classification as an EU Allergen and prohibition as a fragrance ingredient, lead us to advise against its inclusion in precision skincare formulations.
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References
Sources
- thegoodscentscompany.com ↗
- brieflands.com ↗
- nih.gov ↗
- ijabbr.com ↗
- inolex.com ↗
- biointerfaceresearch.com ↗
- mdpi.com ↗
- typology.com ↗
- imist.ma ↗
- cosmileeurope.eu ↗
- specialchem.com ↗
- kaplanmd.com ↗
- europa.eu ↗
- ewg.org ↗
- skinsort.com ↗
- fda.gov ↗