Science
Mechanism of Action
This ferment filtrate acts as a natural antimicrobial agent by releasing a peptide and lactic acid, which collectively inhibit the proliferation of various bacteria, molds, and yeasts. It strategically supports a balanced skin microbiome, targeting detrimental microorganisms while fostering beneficial ones. Beyond its preservative qualities, it draws and retains moisture as a humectant, enhancing skin hydration, elasticity, and softness, while also fortifying the skin barrier. It further contributes to skin homeostasis by balancing pH, calming irritation, and alleviating inflammation.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 Demonstrated Minimum Inhibitory Concentrations (MIC) against A. brasiliensis, C. albicans, S. aeruginosa (0.25-2%), E. coli (0.50-4%), and P. aeruginosa (1-4%).
- 02 Effectively inhibited microbial growth in a cream base against a spectrum of microorganisms including S. aureus, E. coli, P. aeruginosa, C. albicans, and A. niger.
- 03 Proven non-sensitizing in a human repeated insult patch test (HRIPT) with 50 subjects at a 10% dilution, and in a formulation at 0.04% with 105 subjects.
- 04 Evaluated as non-photoirritating in an irradiated EpiDerm reconstructed epidermis model.
Transparency
Dusting Analysis
The available research data does not indicate that Leuconostoc Ferment Filtrate is commonly subject to cosmetic dusting concerns or specifies any relevant thresholds.
The Formula
Formulation
Stability
The ingredient exhibits general stability up to 60-70°C and maintains activity across a broad pH range of 3.0 to 8.0, with activity diminishing at pH 9. Optimal performance is often cited by suppliers within a narrower pH band of 4.0-6.0. It should be stored sealed, away from sunlight, at room temperature, and not frozen. Sedimentation may occur, requiring thorough mixing before use. It may impart a slight color to clear cosmetic preparations. Formulations highly susceptible to mold or yeast growth might require supplementary fungal protection.
Safety
Safety Profile
The CIR Expert Panel affirmed its safety in cosmetics at current use concentrations, provided formulations are non-sensitizing. Its origin from edible radish roots and fermentation with GRAS-status lactic acid bacteria (Leuconostoc strains) suggests low systemic or dermal toxicity. While reported use reaches 1.1% in cleansing products, leave-on dermal exposure has a reported maximum of 0.03% in face and neck spray formulations. Clinical studies at 10% (dilution) and 0.04% (in formulation) showed no sensitization.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Leuconostoc Ferment Filtrate is a valuable multifunctional ingredient, offering natural preservation, significant moisturizing benefits, and skin conditioning with a robust safety and compatibility profile across all skin types.
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