Science
Mechanism of Action
LAVANDULA DENTATA FLOWER/LEAF OIL achieves its benefits through a synergistic action of its primary chemical constituents, including linalool (up to 47.30%), camphor (up to 18.3%), eucalyptol (up to 33.1%), fenchone (up to 15.6%), and linalyl acetate (up to 28.65%). These compounds collectively contribute to its broad-spectrum antimicrobial efficacy against bacteria and various fungal strains, while also providing significant antioxidant protection against free radical damage. The oil's anti-inflammatory capabilities contribute to its soothing profile, notably without damaging the fungal cell wall or plasma membrane in its antifungal action against Candida albicans.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Demonstrated antibacterial activity against diverse Gram-positive and Gram-negative bacteria, with minimal inhibition concentrations (MIC) reported between 0.1 and 0.6 μg/mL (0.00001% - 0.00006%).
- 02 Inhibited mycelial growth of Aspergillus carbonarius by 63.7% at a 0.1% concentration. It achieved 100% inhibition of Botrytis cinerea mycelial growth across concentrations of 5, 10, and 40 μg/mL (0.0005% - 0.004%). Potent fungicidal activity against oral Candida albicans, including miconazole-resistant isolates, was observed at 8 μg/mL (MIC100) and 16 μg/mL (MFC). Partial antifungal activity against Alternaria alternata was noted at 40 μg/mL.
- 03 Exhibited significant antioxidant activity, evidenced by IC50 values for DPPH radical scavenging at 12.95 ± 1.300 mg/mL (approximately 1.3%) and EC50 values for FRAP at 11.88 ± 0.23 mg/mL (approximately 1.19%).
Transparency
Dusting Analysis
As an oil-soluble liquid, LAVANDULA DENTATA FLOWER/LEAF OIL does not present dusting concerns typical of powdered ingredients during manufacturing or application.
The Formula
Formulation
Stability
Being a hydrophobic liquid, this essential oil's stability can be compromised by air exposure. Key components such as linalyl acetate and linalool are susceptible to autoxidation, which can lead to the formation of contact allergens over time. It demonstrates excellent compatibility with various essential oils, including Bergamot, Eucalyptus, Geranium, Lemon, Rosemary, and Tea Tree.
Synergies
- Bergamot oil
- Citronella oil
- Clary Sage oil
- Eucalyptus oil
- Geranium oil
- Grapefruit oil
- Hyssop oil
- Juniper Berry oil
- Lemon oil
- Lime oil
- Patchouli oil
- Peppermint oil
- Pine oil
- Rosemary oil
- Spearmint oil
- Tangerine oil
- Tea Tree oil
Safety
Safety Profile
The CIR Expert Panel indicated in 2015 that LAVANDULA DENTATA (LAVENDER) OIL was not comprehensively reviewed nor listed in the INCI Dictionary. Essential oils, including this species, are generally recognized for their potential to induce irritant or allergenic skin reactions due to constituents like linalool and linalyl acetate. While direct data for this specific oil's cytotoxicity to human skin is limited, similar species like Lavandula angustifolia have shown in vitro cytotoxicity at 0.25% (v/v). High doses should be avoided during pregnancy. For topical application, proper dilution with a carrier oil and prior patch testing are strongly recommended to mitigate potential adverse reactions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite its promising antimicrobial and antioxidant efficacy demonstrated in vitro, the lack of a comprehensive CIR safety review, coupled with a medium irritancy risk and potential for autoxidation-induced allergens, positions LAVANDULA DENTATA FLOWER/LEAF OIL as a questionable choice for precision skincare, particularly for sensitive skin types.
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