Science
Mechanism of Action
As an anionic surfactant, Lauroyl Sarcosine (typically used as its sodium salt, Sodium Lauroyl Sarcosinate) functions by lowering surface tension, facilitating the emulsification of oil and dirt with water for effective rinsing. Its amphiphilic nature, possessing both hydrophilic and hydrophobic characteristics, allows it to condition the skin by forming a protective layer that retards moisture loss from the epidermal surface. Furthermore, this ingredient demonstrates inherent antimicrobial properties, contributing to the inhibition of bacterial growth on the skin.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Non-irritating and non-sensitizing in rinse-off products (referring to Sodium Lauroyl Sarcosinate).
- 02 Non-irritating and non-sensitizing in leave-on products (referring to Sodium Lauroyl Sarcosinate).
- 03 Retarded moisture loss from the skin by forming a hydrophobic protective layer on the epidermal surface (referring to Cocoyl Sarcosine and Sodium Lauroyl Sarcosinate).
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Lauroyl Sarcosine, primarily as Sodium Lauroyl Sarcosinate, is stable within a pH range of 5-9. The carboxylate group of Sodium Lauroyl Sarcosinate becomes negatively charged above approximately pH 5.5, while the amide linkage nitrogen remains neutrally charged across this pH spectrum.
Conflicts
- Strong oxidizing agents
- Ingredients whose safety is based on lack of dermal absorption, due to Lauroyl Sarcosine's ability to enhance skin penetration
- Nitrosating agents, which could lead to the formation of N-nitrososarcosine (a known animal carcinogen)
Safety
Safety Profile
The CIR Expert Panel determined fatty acyl sarcosines and their salts (including Lauroyl Sarcosine) are safe when formulated to be non-irritating, specifically up to 15% in rinse-off products and 5% in leave-on products. Strict caution is advised against co-formulation with nitrosating agents to prevent the formation of N-nitrososarcosine. Its capacity to enhance skin penetration necessitates careful consideration when formulating with ingredients whose safety is contingent on minimal dermal absorption. Safety for inhaled products is currently unknown. The FDA recognizes Lauroyl Sarcosine as a Food Contact Substance.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Lauroyl Sarcosine is a valuable ingredient, effectively cleansing and conditioning across all skin types, with its moisture-retentive and antimicrobial benefits making it a strong asset in formulations that adhere strictly to its precise safety and compatibility guidelines.
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