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LACTOSCATONE.

Questionable CAS 21280-29-5 / PERFUMING

Lactoscatone is a synthetic aromatic compound recognized for its complex fragrance profile. It contributes warm, milky, woody animalic notes, evoking natural musk, sandalwood, and the richness of gardenia and tuberose flowers, primarily enhancing sensory experience in formulations.

Fragrance

Science

Lactoscatone functions exclusively as a fragrance ingredient by delivering a sophisticated olfactory experience. It does not exhibit any known biological mechanism of action or direct therapeutic benefits for skin health or function.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Commonly dusted
Min. effective
0.02%
Red flag below
0.02%

As a pure fragrance ingredient, Lactoscatone offers no direct active benefits for the skin. Its inclusion above the recommended safe limit of 0.02% in general finished products may elevate the risk of irritation and sensitization without contributing to skincare efficacy.


The Formula

Solubility
Oil
Optimal pH 2 – 10
0 7 14

Stability

Lactoscatone demonstrates robust stability across a broad pH range (2-10), maintaining integrity in diverse product types, including shampoos (pH 6), soaps (pH 9-10), body lotions (pH 6.5), and acidic cleaners (pH 2). It is stable in alcohol-based sprays and oil-in-water emulsions, offering excellent substantivity on both skin and hair.

Conflicts

  • bleach

Safety

CIR Status
Not reviewed
Max tested
0.02%
Sensitization risk Moderate

The Expert Panel for Fragrance Safety (RIFM) deemed Lactoscatone safe within specified limits, showing no cytotoxicity or genotoxicity in BlueScreen assays and no expected phototoxicity or photoallergenicity. However, European safety information highlights potential irritation to eyes, respiratory system, and skin (R 36/37/38), and a risk of sensitization by skin contact (R 43). It is also classified as harmful if swallowed (H302). Maximum acceptable concentrations are 0.07% for lip products and 0.02% for other finished products.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

While Lactoscatone contributes a desirable scent profile, it offers no direct benefits for skin health and presents a moderate risk of irritation and sensitization, particularly for sensitive individuals or at concentrations exceeding 0.02%.


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