Science
Mechanism of Action
As a fermented ingredient, Lactobacillus/Wine Extract Ferment Filtrate introduces beneficial postbiotics to the skin. The Lactobacillus component meticulously works to balance the skin's microbiome by fostering beneficial bacteria and bolstering the skin's intrinsic defenses. This action directly contributes to enhanced skin barrier function, improves epidermal hydration through its humectant properties, and provides a calming effect that mitigates inflammation and irritation. It also facilitates cellular renewal, helps to maintain optimal skin pH, functions as a natural antioxidant, and exhibits antimicrobial capabilities against detrimental bacteria and fungi. The fermentation process yields vital compounds such as amino acids, peptides, organic acids (notably lactic acid), enzymes, and various antioxidants. Concurrently, the wine extract contributes its own rich array of antioxidants, including polyphenols, alongside organic acids like lactic, malic, and tartaric acids. These elements collectively offer mild exfoliation and further pH balancing advantages, promoting a refined and healthier skin texture.
Research
Clinical Evidence
Medium confidence1%
Key findings
- 01 In a small in-vivo study with 5 participants, Lactobacillus Ferment Lysate Filtrate demonstrated a 47% reduction in skin redness.
- 02 Lactobacillus ferment was shown to reduce skin sensitivity, while 5% exhibited anti-acne efficacy.
- 03 General Lactobacillus extract can stimulate beta-defensin production in skin cells, decrease inflamed and non-inflamed acne lesions, and diminish skin sensitivity (e.g., lactic acid stinging).
Transparency
Dusting Analysis
While some low-level benefits, such as beta-defensin stimulation, may occur at concentrations as low as 0.001%, clinical studies demonstrating significant reductions in redness, anti-acne effects, or noticeable reductions in skin sensitivity indicate effective concentrations typically range from 1% to 5%. Formulations utilizing this ingredient below 1% for major claims of clinical efficacy are likely to be suboptimal.
The Formula
Formulation
Stability
This ingredient maintains optimal stability within a pH range of 3 to 7. It can be directly incorporated into aqueous formulations, provided the temperature remains below 50°C. When considered as a natural preservative, it may necessitate complementary preservative strategies or pH management for comprehensive broad-spectrum protection.
Safety
Safety Profile
The CIR Expert Panel affirmed the safety of Lactobacillus Ferment and its filtrates/lysates in cosmetic applications. It is generally regarded as non-toxic, non-sensitizing, and non-comedogenic. However, a minor risk of allergic reaction exists for individuals with particularly sensitive skin, warranting a patch test. It is important to note that postbiotics such as lactic acid, a byproduct of Lactobacillus fermentation, are known tyrosinase-inhibitors and could potentially contribute to skin depigmentation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This fermented filtrate offers a robust portfolio of benefits, including microbiome balance, barrier enhancement, and proven soothing and anti-acne properties, making it a highly valuable and versatile component for diverse skincare formulations.
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