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Moumoujus

LACTOBACILLUS/TURMERIC FERMENT FILTRATE.

Valuable / HUMECTANT

Lactobacillus/Turmeric Ferment Filtrate is a biotechnologically enhanced ingredient derived from turmeric, fermented using Lactobacillus bacteria. This innovative process significantly boosts the bioavailability and potency of turmeric's beneficial compounds, delivering advanced antioxidant, anti-inflammatory, and microbiome-balancing properties to the skin.

Summary

Antioxidant Skin-soothing Anti-inflammatory Skin-conditioning Antimicrobial Hydrating Promotes skin microbiome balance Strengthens skin barrier Skin repair and rejuvenation pH balancing

Science

Mechanism of Action

This ferment filtrate functions multifacetedly within the skin. The fermentation process enhances the availability of key turmeric compounds, such as curcumin, which act as potent antioxidants, effectively neutralizing free radicals and inhibiting oxidative reactions. Its anti-inflammatory action is evidenced by its ability to suppress the c-Jun N-terminal kinase (JNK) pathway, reduce nitrite levels, and downregulate inflammatory markers like TNF-α and TLR4, thereby soothing irritated skin. The ingredient also exhibits antimicrobial properties, assisting in the control of skin microorganisms implicated in conditions like acne. Furthermore, it supports skin barrier integrity, contributes to repair and rejuvenation, and helps maintain a balanced skin microbiome and optimal pH by introducing beneficial metabolites, including lactic acid and peptides. Its humectant qualities additionally enhance skin hydration.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Fermentation with Lactobacillus fermentum increased curcumin content by 9.76%. Demonstrated no cytotoxicity and promoted cell survival in LPS-induced RAW 264.7 cells. Exhibited antioxidant activity with 7.88 ± 3.36% DPPH scavenging and significant anti-inflammatory effects through reduced nitrite levels and suppressed TNF-α and TLR4 expression, mediated via the c-Jun N-terminal kinase (JNK) signal pathway.
  2. 02 Lactobacillus Ferment Lysate Filtrate, a related ingredient, showed a 47% reduction in redness in an in-vivo study involving 5 participants.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

For optimal stability, this ingredient should be incorporated directly into aqueous formulas at temperatures below 50°C. The fermentation process is noted to increase the solubility of curcumin, a key compound of turmeric, which is typically poorly water-soluble.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
1.5%
Sensitization risk Low

The CIR Expert Panel has deemed Lactobacillus Ferment and its related filtrates/lysates safe for use in cosmetics. These ingredients are generally predicted to be non-irritating and non-sensitizing based on extensive in vitro assays and Human Repeat Insult Patch Tests (HRIPTs) for similar ferment filtrates (e.g., up to 10% for Lactobacillus Ferment). However, due to potential individual sensitivities, patch testing is recommended. While the ingredient may inhibit tyrosinase activity, formulators are advised not to use it for skin depigmentation, as this effect is considered a drug claim.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

This fermented turmeric filtrate is a valuable multi-functional ingredient, offering enhanced bioavailability of beneficial compounds for antioxidant, anti-inflammatory, and microbiome-balancing effects with a favorable safety profile.

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