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L-ALLO-OCIMENOL.

Valuable CAS 126-90-9 / PERFUMING

L-ALLO-OCIMENOL, a terpene alcohol often discussed in the context of Linalool due to similar chemical structure and properties, primarily serves as a fragrance ingredient in cosmetics. Beyond its aromatic contribution, this compound demonstrates multiple skin benefits, including antimicrobial, anti-inflammatory, and antioxidant actions, and can facilitate the absorption of other actives. Due to its potential for sensitization, especially when oxidized, its use is carefully regulated by international bodies.

perfuming deodorant antimicrobial antifungal anti-inflammatory antioxidant penetration enhancer preservative booster

Science

This ingredient functions by inhibiting the growth of harmful bacteria and fungi, including P. acnes, thus contributing to a balanced skin microflora and serving as a preservative booster. It calms UV-induced irritation, visibly reducing redness and discomfort through its anti-inflammatory action. Furthermore, L-ALLO-OCIMENOL provides antioxidant defense against free radicals and oxidative stress, and has been observed to improve the skin's absorption and penetration of various active ingredients.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 6 – 7.5
0 7 14

Stability

L-ALLO-OCIMENOL is relatively stable in alkali, but prone to degradation in acidic or very alkaline environments. It is susceptible to isomerization and readily oxidizes upon air exposure, leading to the formation of allergenic hydroperoxides. To maintain stability, formulations should incorporate antioxidants (e.g., BHT, BHA, tocopherol), be stored in airtight containers with minimal headspace, and consider inert gas purging.

Synergies

  • improved absorption and penetration of other active ingredients

Conflicts

  • strong oxidizing agents
  • acidic conditions
  • very alkaline conditions
  • air exposure (leads to oxidation)

Safety

CIR Status
Safe with restrictions
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel defers to the International Fragrance Association (IFRA) program for fragrance ingredients, where IFRA restricts Linalool's use due to potential sensitization. The SCCS (Scientific Committee on Consumer Safety) considers L-ALLO-OCIMENOL (as Linalool) safe for cosmetic products when declared on the ingredient list if exceeding 0.001% in leave-on products and 0.01% in rinse-off products. While natural Linalool up to 20% was not found to be a sensitizer, oxidized Linalool hydroperoxides at 1.0% demonstrated a 5.9% to 6.9% positive reaction rate in patch tests on dermatitis patients, confirming its sensitizing potential upon oxidation. Higher concentrations, such as 32%, have been described as moderately irritating.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Valuable

L-ALLO-OCIMENOL offers valuable multi-functional benefits, including antimicrobial and antioxidant support; however, its application demands precise formulation control and stabilization to mitigate its moderate sensitization and irritation risks, particularly for reactive skin types.


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