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Moumoujus

KOCHIA SCOPARIA FRUIT POWDER.

Valuable / ABRASIVE, SKIN PROTECTING

Derived from the fruit of the Kochia scoparia plant, this botanical ingredient offers significant anti-inflammatory and soothing benefits. It actively works to reduce skin irritation, redness, and discomfort, making it particularly beneficial for calming reactive and sensitive skin conditions.

Summary

Skin conditioning

Science

Mechanism of Action

Kochia Scoparia Fruit Powder exerts its anti-inflammatory effects by modulating critical pathways involved in skin inflammation. It inhibits the production of key pro-inflammatory cytokines such as IL-1β and TNF-α mRNA, and suppresses inflammatory mediators like PGE2, iNOS, and COX-2 proteins. Furthermore, it interferes with NF-κB expression and mitigates MAPK signaling pathways (ERK1/2, p38, JNK), thereby reducing epidermal and dermal hyperplasia, immune cell infiltration, and allergic responses. These actions contribute to its traditional use in alleviating various skin inflammations and pruritus.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A 1% topical application of Kochia scoparia water extract (KSW) significantly alleviated atopic dermatitis-like symptoms in mice, demonstrating reduced epidermal and dermal thickening, alongside a decrease in pro-inflammatory cytokine mRNA levels (IL-1β, TNF-α).
  2. 02 Topical application of methanol extracts derived from K. scoparia dried fruit effectively inhibited ear thickness, weight increases, epidermal acanthosis, spongiosis, and immune cell infiltration in mice with contact dermatitis, while also reducing TNF-α, IFN-γ, and MCP-1 in inflamed tissues.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While formal safety assessments by CIR, SCCS, or FDA are not yet available, Kochia Scoparia has a rich history of over 2000 years of traditional topical use in Chinese and Korean medicine for various skin conditions. Animal studies on oral administration have shown a low acute toxicity, with an LD50 of 7.15 ± 0.03 g/kg for a water extract in mice. EWG Skin Deep rates Kochia Scoparia Fruit Extract with a 'LOW' hazard for concerns including cancer, allergies & immunotoxicity, and developmental and reproductive toxicity.

Your Skin

Skin Compatibility

Yes Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Kochia Scoparia Fruit Powder is a valuable botanical ingredient, with its extracts demonstrating potent anti-inflammatory and soothing properties in preclinical studies, making it promising for calming sensitive and irritated skin.

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