Science
Mechanism of Action
The ingredient functions by delivering a complex profile of fermentation byproducts, including intracellular and extracellular metabolites, enzymes, peptides, teichoic acids, polysaccharides, and organic acids such as lactic acid. Specifically, the Lactobacillus components are recognized for their ability to facilitate DNA repair, provide robust protection against environmental aggressors, and exert significant antimicrobial and anti-inflammatory effects. It actively contributes to balancing the skin's microflora, which is particularly beneficial for mitigating issues like acne and rosacea. Furthermore, it stimulates the production of beta-defensins in skin cells, forms a protective film to reduce transepidermal water loss, strengthens the skin cuticle, and helps to balance cutaneous water and oil levels. Certain postbiotics within this ferment may also act as tyrosinase-inhibitors, offering a potential mechanism for skin depigmentation.
Research
Clinical Evidence
Medium confidence5%
Key findings
- 01 Lactobacillus ferment demonstrated effective anti-acne properties.
- 02 Lactobacillus ferment was observed to reduce skin sensitivity.
- 03 An in-vivo study (n=5) of Lactobacillus Ferment Lysate Filtrate showed a 47% reduction in skin redness.
Transparency
Dusting Analysis
Data is not available regarding the ingredient's propensity for 'dusting' or its typical concentration in formulations.
The Formula
Formulation
Safety
Safety Profile
While the complete KLUYVEROMYCES/LACTOBACILLUS/BRASSICA NAPUS SEED OIL FERMENT FILTRATE has not been individually assessed by the CIR Expert Panel, its key components, such as Lactobacillus Ferment and related filtrates (Lactobacillus Ferment Filtrate, Lactobacillus Ferment Lysate, and Lactobacillus Ferment Lysate Filtrate), have been concluded as 'safe as used in cosmetics'. In vitro dermal and ocular irritation assays for Lactobacillus Ferment Lysate Filtrate demonstrated non-irritating results, and no genotoxicity was observed in Ames assays for related Lactobacillus ferment components. The highest reported concentration for Lactobacillus Ferment alone in face and neck products is up to 5.6%.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multi-functional ferment filtrate offers significant benefits for balancing skin microflora, reducing inflammation and acne, and enhancing skin's natural defenses, making it a valuable addition for diverse skin concerns.
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References
Sources