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KEPHALIS.

Optional CAS 36306-87-3 / PERFUMING

Kephalis is a synthetic aroma compound designed to impart a distinct woody, amber, and tobacco scent to formulations. Primarily valued for its olfactive contribution, this ingredient does not possess known biological activity or offer direct skincare benefits.

fragrance

Science

Kephalis functions solely as a sensory agent, delivering a sophisticated fragrance profile without engaging in specific biological pathways or providing functional effects on skin health.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Kephalis is typically supplied as a liquid, therefore 'dusting' as a powder concern is not applicable to this ingredient.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Kephalis demonstrates good stability across various matrices, including alcoholic perfumes, fabric conditioners (pH 3), shampoos (pH 6), and soaps (pH 10). Moderate stability is noted in antiperspirant (pH 3.5) and at pH 2, while poor stability occurs in liquid bleach and antiperspirant sprays. For optimal integration, add in the final formulation step, avoid temperatures above 40°C, and store in cool, dry, tightly sealed containers protected from heat and light.

Conflicts

  • strong acids
  • alkalis
  • oxidizing agents
  • extreme heat

Safety

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Low

Kephalis is deemed safe for use within IFRA (International Fragrance Association) recommended limits, with the 50th Amendment indicating no restrictions. Although some Safety Data Sheets (SDS) classify it as potentially causing skin irritation (H315), human experience data from a 10% solution indicated no irritation or sensitization. It has not undergone specific review by CIR or SCCS and is not listed by the FDA for food or drug uses.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Optional

Kephalis is a safe and low-irritancy synthetic fragrance ingredient that enhances product appeal through scent, without contributing active skincare benefits.


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