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Moumoujus

JUNIPERUS OXYCEDRUS WOOD OIL.

Insufficient Data CAS 90046-02-9 / FRAGRANCE, PERFUMING, TONIC

Juniperus Oxycedrus Wood Oil, also known as Cade oil, is an essential oil extracted from the wood of the Juniperus oxycedrus tree. It is valued in skincare for its antiseptic, anti-inflammatory, antimicrobial, and antioxidant properties. This ingredient is commonly utilized for its purifying and sebum-regulating effects, making it particularly relevant for addressing concerns associated with oily and acne-prone skin.

Summary

Antiseptic Anti-inflammatory Antimicrobial Antioxidant Sebum-regulating Exfoliant Masking Perfuming Tonic

Science

Mechanism of Action

This wood oil exerts its effects through multiple mechanisms. It demonstrates antiseptic and antimicrobial activity, contributing to the reduction of various bacteria and fungi on the skin's surface. Its anti-inflammatory and antioxidant compounds work to soothe irritation and protect against oxidative stress. Furthermore, it functions as a sebum-regulating agent, helping to balance natural oil production, and acts as an exfoliator by promoting the shedding of superficial skin cells, which can assist in conditions like dandruff.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro assessments indicated potent antibacterial activity against Gram-positive bacteria, effective within a concentration range of 0.25% to 2% v/v. Activity against Salmonella spp. was observed at 4% v/v.
  2. 02 Fungicidal efficacy was demonstrated in vitro, with particularly strong activity against Candida auris sessile cells, across concentrations from 0.045% to 12.5% v/v.
  3. 03 An in vivo study conducted on rats revealed significant antioxidant and anti-inflammatory benefits. Cade oil effectively reduced inflammatory cell recruitment, enhanced antioxidant status, and ameliorated histopathological changes within an allergic asthma model.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Juniperus Oxycedrus Wood Oil, being a highly concentrated essential oil, is not water-soluble. For safe topical application, it must be properly diluted in a carrier oil (e.g., vegetable oil), an alcoholic base, or a cleansing formulation such as shampoo or shower gel. Applying the undiluted essential oil, particularly directly into water, poses a risk of skin irritation.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that available data are insufficient to assess the safety of Juniperus Oxycedrus Tar (often considered synonymous) and related juniper ingredients in cosmetic formulations. The tar form specifically has shown genotoxic effects in various assays. While some clinical tests for certain juniper oils indicated no dermal irritation or sensitization, there is documented evidence of sensitization linked to the tar form. Comprehensive data, including irritation, sensitization, and a 2-year dermal carcinogenicity assay for Juniperus Oxycedrus Tar, are needed. Data from related oils cannot be directly extrapolated, and a possibility of skin sensitization should be considered.

Your Skin

Skin Compatibility

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Despite demonstrating promising in vitro antimicrobial, antioxidant, and anti-inflammatory properties, the safety profile of Juniperus Oxycedrus Wood Oil in cosmetic applications is currently hampered by insufficient CIR data, with concerns regarding potential genotoxicity and sensitization, necessitating a cautious approach.

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