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ISOPROPYLMETHYLHEXENAL.

Questionable CAS 35158-25-9 / PERFUMING

ISOPROPYLMETHYLHEXENAL is an aromatic aldehyde valued primarily for its powerful and diffusive fragrance profile, which includes herbaceous, minty, woody-lavender, and subtle fruity notes. While extensively used as a scent component in personal care products, current scientific literature does not attribute direct therapeutic skincare benefits to this ingredient.

Fragrance

Science

This compound's primary mechanism within skincare formulations is its contribution to the product's olfactive profile. No specific biological pathways have been identified through which ISOPROPYLMETHYLHEXENAL provides direct anti-aging, moisturizing, or other targeted skin benefits upon topical application.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient demonstrates stability under typical conditions. For optimal preservation, it should be stored in a cool, dry environment within tightly sealed containers, shielded from heat and light.


Safety

CIR Status
Not reviewed
Sensitization risk Moderate

The Research Institute for Fragrance Materials (RIFM) has published a peer-reviewed safety assessment concluding this ingredient is safe for use as described. While read-across data indicated a potential for skin sensitization with a No Expected Sensitization Induction Level (NESIL) of 590 μg/cm2, a human maximization test conducted in 1972 found no sensitization reactions. However, Globally Harmonized System (GHS) classifications highlight its potential to cause skin irritation (H315) and serious eye irritation (H319). Maximum acceptable concentrations in finished products are determined by systemic toxicity and skin sensitization endpoints.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

This ingredient primarily serves as a fragrance, offering no identified direct skincare benefits, and carries a moderate risk of irritation, rendering its utility in precision skincare formulations questionable.


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