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ISOPROPYLIDENEDIPHENYL BISOXYHYDROXYPROPYL METHACRYLATE/TMDI COPOLYMER.

Avoid CAS - / FILM FORMING

This specialized copolymer primarily acts as a film-forming agent, creating a resilient, continuous layer. Its main applications are in nail care, where it enhances durability and adhesion by covalently bonding to keratin. Due to significant sensitization potential, it is not recommended for direct skin contact in skincare formulations.

Film Forming

Science

This copolymer functions by forming a continuous, protective film upon application to surfaces such as skin, hair, or nails. In its predominant use within nail enhancement systems, it is engineered to establish covalent bonds with keratin, the primary protein in nails. This interaction significantly improves the adhesion and mechanical durability of nail enhancements, contributing to their long-lasting integrity and flexibility.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

This ingredient is a copolymer primarily utilized in nail enhancement products as a film-forming agent, and is not typically associated with 'dusting' in the context of precision skincare formulations.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While technically soluble in water at 3 mg/L at 37 °C, indicating very low aqueous solubility, specific optimal pH ranges for stability have not been identified. Care must be taken to avoid combining this ingredient with other known irritants due to potential synergistic effects that could increase adverse reactions.

Conflicts

  • Other problematic ingredients (risk of increased irritation)

Safety

CIR Status
Safe with restrictions
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed this ingredient, along with related methacrylate esters, safe for use in nail enhancement products, provided formulations are explicitly labeled to prevent skin contact. This critical restriction stems from strong evidence identifying methacrylates as potential human skin toxicants or allergens, posing a high sensitization risk. Consequently, EWG classifies this ingredient with a 'HIGH' use restriction and considers it 'Unacceptable' for EWG VERIFIED products. Direct FDA status for this specific copolymer in cosmetics has not been found, though related methacrylates have indirect food additive listings.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Given its high sensitization potential and explicit recommendations to avoid skin contact, this ingredient is unsuitable and should be avoided in precision skincare formulations designed for direct dermal application.


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