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ISOPROPYLAMINE.

Avoid CAS 75-31-0 / BUFFERING

Isopropylamine is a highly alkaline (pKa 10.63) and volatile liquid, chemically stable but notably flammable. Its primary utility in formulations is pH adjustment, however, its severe corrosive properties present significant safety concerns for direct cosmetic application.

pH adjuster

Science

Isopropylamine functions as a potent pH adjuster due to its strong alkaline nature, characterized by a pKa of 10.63. This property allows it to effectively increase the pH of a formulation, moving it towards a more alkaline state.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

This hygroscopic, colorless, and volatile liquid is chemically stable but notably flammable, necessitating appropriate storage and handling.

Conflicts

  • acids (forms salts)
  • perchloryl fluoride (violent oxidation/explosion)
  • 1-chloro-2,3-epoxypropane (violent exothermic reaction)
  • strong oxidizers

Safety

CIR Status
Not reviewed
Sensitization risk High

The Cosmetic Ingredient Review (CIR) has not specifically assessed Isopropylamine for cosmetic use. However, the substance is classified as corrosive to eyes, skin, and the respiratory tract, with direct contact capable of causing severe irritation, burns, and dermatitis upon repeated exposure.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Isopropylamine is an ingredient of significant concern for cosmetic formulations due to its inherent corrosive nature and potential for severe skin and eye irritation, rendering its inclusion highly questionable for direct application in skincare.


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References