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Moumoujus

ISOPROPYL-P-CRESOL.

Optional CAS 4427-56-9 / PERFUMING

ISOPROPYL-P-CRESOL is an aromatic compound predominantly utilized for its fragrance contributions in cosmetic formulations. It additionally exhibits potential as a cosmetic biocide and preservative, inferred from the known antimicrobial activity of related cresol isomers. Its integration into skincare is strictly governed by concentration limits to ensure safety.

Summary

fragrance preservative antimicrobial

Science

Mechanism of Action

While primarily incorporated for its distinct scent profile, ISOPROPYL-P-CRESOL's functional mechanism extends to potential antimicrobial activity. Its role as a cosmetic biocide and preservative, particularly regarding antifungal properties, is derived from structural similarities to well-established compounds such as thymol, an isomer recognized for its preservative efficacy.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Chemical analogs like p-Cresol indicate that ISOPROPYL-P-CRESOL may be sensitive to degradation from heat and light exposure. Formulators should also note potential incompatibility with strong oxidizing agents and strong alkalis. Furthermore, it may interact adversely with certain plastics, coatings, and rubber materials, potentially leading to degradation.

Conflicts

  • strong oxidizers
  • strong alkalis
  • some plastics
  • coatings
  • rubber

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
0.5%
Sensitization risk Unknown

The CIR Expert Panel has deemed Isopropyl Cresols, including ISOPROPYL-P-CRESOL, safe for cosmetic use, provided concentrations do not exceed 0.5%. This stringent limit is implemented to mitigate the risk of chemical leukoderma, a potential side effect involving skin depigmentation.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Optional

ISOPROPYL-P-CRESOL is an optional ingredient primarily contributing fragrance, with potential secondary preservative benefits, strictly limited to a maximum concentration of 0.5% to prevent the risk of skin depigmentation.

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