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ISOPROPYL-METHYLCYCLOHEXANONE.

Questionable CAS 499-70-7 / PERFUMING

Isopropyl-methylcyclohexanone is a synthetic cyclic ketone primarily employed as a perfuming and flavoring agent in various consumer products. Its principal role in cosmetic formulations, including skincare, is to impart scent.

perfuming

Science

The precise mechanism by which Isopropyl-methylcyclohexanone interacts with skin cells or contributes to any specific dermatological benefit remains unstudied and currently unknown.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Max tested
0.00064%
Sensitization risk Moderate

No specific safety assessment from the Cosmetic Ingredient Review (CIR) or Scientific Committee on Consumer Safety (SCCS) has been identified. While the FDA lists it as a flavoring agent, IFRA standards impose significant restrictions on its use in cosmetic products due to documented concerns regarding dermal sensitization and potential systemic toxicity. Maximum permitted concentrations vary considerably by product category, with the most restrictive for leave-on products being 0.00064% in baby products (Category 5D), up to 1.9% in fine fragrances (Category 4).


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Questionable

As an ingredient primarily for perfuming with identified dermal sensitization risks, potential systemic toxicity, and no demonstrated skin benefits, Isopropyl-methylcyclohexanone is considered questionable for precision skincare formulations.


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