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Moumoujus

ISOPROPYL LANOLATE.

Valuable CAS 63393-93-1 / ANTISTATIC, BINDING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

Isopropyl Lanolate is a sophisticated emollient and skin conditioning agent derived from lanolin. It is recognized for its ability to impart a smooth, soft texture and establish a protective barrier, thereby mitigating trans-epidermal moisture loss.

Summary

antistatic binding emollient emulsifying skin conditioning

Science

Mechanism of Action

Functioning as an emollient and lubricant, Isopropyl Lanolate creates a subtle, protective film on the skin's surface. This action effectively conditions the skin, promoting a soft, smooth, and subtly glossy appearance while actively working to prevent moisture evaporation.

Research

Clinical Evidence

High confidence
Effective range 0.5–10%
Optimal

N/A

Key findings

  1. 01 In a controlled study involving a 2% concentration within a skincare cream moisturizer, one out of thirteen subjects reported irritation after 21 days of application (daily, five days a week).
  2. 02 Human patch tests employing cosmetic formulations at 6% and 14% concentrations demonstrated 'very slight irritating' potential in some subjects, though no instances of contact allergy sensitization were identified across the three formulations tested.
  3. 03 Recommended integration levels for diverse skincare formulations, including creams, lotions, and color applications, typically range from 0.5% to 10.0%, with 1% to 5% being a commonly suggested range for general cosmetic use.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient should not be subjected to temperatures exceeding 80°C for extended durations. Optimal stability is maintained under cool storage conditions. Light syneresis, characterized by the separation of low molecular weight esters, may manifest under specific storage circumstances; however, homogeneity can be re-established by melting the material.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
6%
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has consistently deemed Isopropyl Lanolate safe for cosmetic applications, reaffirming its safety status in 1980, 2001, and 2023. While generally well-tolerated, the Panel specifically noted a concern regarding skin sensitization observed in two out of 53 subjects in one particular study, advocating for continued vigilance. The maximum reported concentration for dermal contact products (e.g., eyeliners) is 6%, though usage up to 14.5% is reported in products with incidental ingestion (e.g., lipsticks).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Isopropyl Lanolate is a valuable emollient, offering significant benefits for improving skin hydration and texture, though its documented potential for mild irritation or sensitization in a small proportion of individuals warrants careful consideration, especially for sensitive skin types.

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