Science
Mechanism of Action
Isopropyl Cresols function as effective cosmetic biocides and preservatives by disrupting microbial integrity, inhibiting the proliferation of both bacteria and fungi within formulations. Furthermore, certain derivatives within this group have been noted to potentially augment the dermal penetration of other cosmetic agents.
Research
Clinical Evidence
High confidence0.1%
Key findings
- 01 The CIR Expert Panel assessed Isopropyl Cresols, including o-Cymen-5-ol and Thymol, as safe for cosmetic use up to 0.5% concentration, specifically to ensure the absence of chemical leukoderma.
- 02 The European Union's Cosmetic Regulation (Annex V) permits o-Cymen-5-ol, a specific Isopropyl Cresol, for use as a preservative at a maximum concentration of 0.1% in cosmetic products.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
o-Cymen-5-ol demonstrates stability when exposed to light but reacts readily with oxidizing agents.
Conflicts
- Oxidizing agents
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Isopropyl Cresols are safe at concentrations up to 0.5% in cosmetics to prevent chemical leukoderma. In the European Union, o-Cymen-5-ol is specifically allowed as a preservative at a maximum concentration of 0.1%. Thymol, another Isopropyl Cresol, holds approval from the FDA as both a direct and indirect food additive.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Isopropyl Cresols are a valuable ingredient due to their effective broad-spectrum antimicrobial and preservative capabilities, ensuring product integrity and freshness with a favorable safety profile at regulated concentrations.
Related
Similar Ingredients
Finding similar ingredients…