Science
Mechanism of Action
Within cosmetic formulations, Isopropyl Citrate functions by chelating metal ions, thereby preventing oxidative reactions and rancidity that can compromise product integrity and the efficacy of active ingredients. It also improves product texture by acting as a plasticiser, making formulations smoother, and as a solvent, aiding in the dissolution and uniform dispersion of other components. These actions indirectly benefit the skin by ensuring the delivery of stable and optimally formulated products.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Isopropyl Citrate exhibits solubility in both organic solvents, water, and ethanol, particularly when used in its mixture form. Its unique structure, derived from water-insoluble citric acid and oil-soluble isopropyl alcohol, enables it to dissolve effectively in oil. Specific optimal pH ranges for its intrinsic stability are not explicitly defined, though citrate buffers typically operate within a pH range of 3.0 to 6.2.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has assessed Isopropyl Citrate, concluding its safety in current cosmetic applications. This assessment primarily focused on dermal toxicity, considering its status as a GRAS (Generally Recognized As Safe) direct human food ingredient by the FDA (21 CFR 184.1386). The Scientific Committee on Consumer Safety (SCCS) has not yet conducted a specific review for its use in cosmetics.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Isopropyl Citrate is a valuable ingredient for enhancing formulation stability, texture, and overall product integrity, ensuring precision skincare products remain effective and pleasant to use.
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