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ISOPROPYL ACETATE.

Optional CAS 108-21-4 / SOLVENT

Isopropyl Acetate is an organic ester primarily utilized in skincare formulations as a solvent, characterized by its potent dissolving capabilities and potential to enhance the skin penetration of other ingredients. It additionally functions as a coupling agent within complex solvent systems and contributes to fragrance profiles.

Solvent Coupling agent Fragrance component

Science

As a primary solvent, Isopropyl Acetate exhibits strong dissolving power, which facilitates the dispersion and incorporation of various ingredients into cosmetic formulations. Its ability to extract substances and permeate the skin suggests a role in optimizing the delivery of active compounds, while also stabilizing diverse solvent mixtures as a coupling agent.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ester can slowly decompose upon contact with steel in the presence of air, yielding acetic acid and isopropanol. Similarly, atmospheric moisture absorption can lead to hydrolysis, breaking it down into isopropanol and acetic acid. Esters generally react exothermically with strong acids and caustic solutions.

Conflicts

  • strong oxidizing materials
  • alkali metals and hydrides (generates flammable hydrogen)
  • strong acids
  • strong alkalis (caustic solutions)
  • many plastics (can attack them)
  • water (leads to decomposition/hydrolysis)

Safety

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) panel has concluded that Isopropyl Acetate is safe for use in cosmetic applications, based on maximum reported 'as used' concentrations. However, explicit concentration limits for cosmetic use were not identified. The FDA also recognizes it as safe for general or specific limited use as a food flavoring agent or adjuvant. There is no specific SCCS opinion available.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Optional

Isopropyl Acetate is an effective solvent and coupling agent for formulation purposes, deemed safe as used by CIR, but it lacks direct skin benefits and has unknown irritancy or comedogenicity, requiring careful formulation.


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