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ISOLONGIFOLANONE.

Avoid CAS 23787-90-8 / PERFUMING

Isolongifolanone is a synthetic aromatic compound primarily employed for its distinctive woody, amber, and earthy scent profile. Beyond its role as a fragrance, it has demonstrated secondary properties as an antimicrobial and insect repellent, though these are not its primary application in skincare.

Fragrance Antimicrobial Insect Repellent Masking Agent

Science

This compound primarily functions by volatile emission, imparting a characteristic fragrance that enhances product sensorial appeal. While noted for potential antimicrobial activity, the specific mechanisms of action and direct benefits to skin health have not been thoroughly elucidated in clinical contexts for topical skincare applications.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Isolongifolanone is primarily a fragrance ingredient; its contribution to direct skin benefits is not established, rendering 'dusting' analysis irrelevant in the context of active ingredient efficacy.


The Formula

Solubility
Oil
Optimal pH 2 – 10.5
0 7 14

Stability

Exhibits robust odor stability across a broad pH spectrum, maintaining integrity from highly acidic (pH 2) to alkaline (pH 10.5) formulations. Its stability significantly diminishes in the presence of strong oxidizers like liquid bleach (pH 11).


Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk High

The Cosmetic Ingredient Review (CIR) has not assessed Isolongifolanone. The European Chemicals Agency (ECHA) classifies it as 'Skin Irrit. 2', indicating it is a skin irritant, and notes it may cause an allergic skin reaction. Maximum recommended usage in body creams/oils/lotions/foot care, per IFRA guidelines, is 1.00%.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

While offering a pleasant aroma, Isolongifolanone is classified as a skin irritant with a high sensitization risk, making it unsuitable for precision skincare formulations where skin health and minimal irritation are paramount.


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