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Moumoujus

ISODECYL ACRYLATE.

Avoid CAS 1330-61-6 / NOT REPORTED

Isodecyl Acrylate is a hydrophobic monofunctional acrylic monomer primarily used in industrial applications such as coatings, adhesives, and sealants. Its specific role and mechanism within cosmetic formulations, particularly for active skin benefits, are not clearly established.

Summary

Science

Mechanism of Action

As a hydrophobic monofunctional acrylic monomer, Isodecyl Acrylate functions by forming polymers, enhancing properties like adhesion and impact resistance in industrial contexts. For topical skin application, its direct mechanism of action or any specific cosmetic benefit is not defined in current literature. Like other acrylates, it is generally metabolized via conjugation with glutathione or hydrolysis by carboxylesterases.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 4 – 7
0 7 14

Stability

Isodecyl Acrylate demonstrates hydrolytic instability at extreme pH levels (e.g., 1.2 and 9) but remains stable within a pH range of 4 to 7. It is highly reactive, prone to polymerization when exposed to heat or light, a process that generates significant heat. Strong oxidants and acids, especially strong oxidizing acids, can trigger vigorous exothermic reactions. Interaction with caustic solutions also produces heat, while mixtures with alkali metals and hydrides yield flammable hydrogen. Optimal storage conditions include a temperature of 4°C in a tightly closed container. Note that phenolic inhibitors, often used for stability, require the presence of oxygen to be effective, making storage under an inert atmosphere counterproductive. Moisture can also initiate rust-catalyzed polymerization.

Conflicts

  • Heat
  • Light
  • Strong oxidants
  • Acids (especially strong oxidizing acids)
  • Caustic solutions
  • Alkali metals
  • Hydrides
  • Absence of oxygen (if phenolic inhibitors are used)
  • Moisture

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Isodecyl Acrylate is classified under the Globally Harmonized System (GHS) as a moderate skin sensitizer (H317), indicating it may cause an allergic skin reaction. It also causes direct skin irritation (H315) and serious eye irritation (H319). Respiratory irritation (H335) can occur, particularly at concentrations of 10% or greater, leading to Specific Target Organ Toxicity – Single Exposure, Category 3. Prolonged dermal contact with the liquid can induce irritation. It is a REACH Registered Substance.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Given the absence of defined cosmetic benefits, classification as a moderate sensitizer, high irritancy potential, and unreviewed CIR status, Isodecyl Acrylate is not recommended for precision skincare formulations.

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