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ISOBUTYLTRIETHOXYSILANE.

Questionable CAS 17980-47-1 / BINDING

Isobutyltriethoxysilane is an organosilicon compound designed to modify surface characteristics, imparting hydrophobicity. In skincare, it functions as a skin-conditioning agent and contributes to film formation on the skin's surface.

Skin-Conditioning Film-forming Surface Modifier

Science

This organosilicon compound operates as a surface modifier by forming silanol groups upon exposure to moisture through hydrolysis. These silanol groups then crosslink to create stable siloxane networks, a process that enhances surface hydrophobicity and facilitates the adhesion of organic materials to inorganic substrates. In cosmetic applications, this mechanism supports its role in conditioning the skin and forming a protective film.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Isobutyltriethoxysilane is highly sensitive to moisture; it undergoes slow decomposition upon contact with humid air or water, releasing ethanol. It requires storage under inert gas and strict protection from moisture to maintain integrity.

Conflicts

  • Oxidizing agents
  • Water (slow decomposition)

Safety

CIR Status
Insufficient data
Sensitization risk Moderate

Although Isobutyltriethoxysilane belongs to the alkoxyl alkyl silane class, for which some members (e.g., Triethoxycaprylylsilane) have been reviewed and deemed safe by the CIR Expert Panel, this specific ingredient has not received an explicit safety conclusion. Safety Data Sheets indicate that it causes skin irritation (Category 2, H315) and serious eye irritation. No specific SCCS or FDA regulatory status for its use in cosmetics was identified.


Your Skin

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Questionable

While Isobutyltriethoxysilane offers beneficial skin conditioning and film-forming properties, its 'insufficient data' status from CIR and reported skin and eye irritation raise significant concerns for use in precision skincare formulations.


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