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Moumoujus

ISOBUTYLATED LANOLIN OIL.

Questionable CAS 85005-47-6 / ANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Isobutylated Lanolin Oil is a derivative of lanolin, prized for its emollient properties that deeply soften and hydrate the skin. It works by forming a protective film on the skin's surface, effectively reducing water loss and maintaining optimal moisture levels.

Summary

Emollient Emulsifying

Science

Mechanism of Action

This ingredient functions as an emollient by establishing an occlusive oil barrier on the stratum corneum, which significantly curtails transepidermal water loss (TEWL). It also actively absorbs trans-epidermal water, behaving like a sponge within the skin's outermost layer to regulate hydration. Furthermore, it possesses emulsifying capabilities and a high spreading coefficient, enhancing formulation characteristics.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 5.5 – 7
0 7 14

Stability

Isobutylated Lanolin Oil is readily soluble in mineral, vegetable, and silicone oils. While generally insoluble in water, it can be miscible with approximately twice its weight in water. The optimal pH range for formulations containing Lanolin materials is between 5.5 and 7.0. It can be susceptible to decomposition in oil-in-water emulsions, yet it functions as an emulsifying agent, contributing to low viscosity and reduced stickiness. It demonstrates good compatibility with most cosmetic formulation substances.

Synergies

  • Mineral oils
  • Vegetable oils
  • Silicone fluids

Conflicts

  • Decomposition risk in oil-in-water emulsions

Safety

Safety Profile

CIR Status
Safe as used
Max tested
65%
Sensitization risk High

The CIR Expert Panel has consistently reaffirmed the safety of Lanolin and related materials, including Lanolin Oil, for topical application, with the most recent tentative report in March 2024 upholding this conclusion. The highest reported use concentration for Lanolin Oil is 65% in lipstick. However, Lanolin was designated the Contact Allergen of the Year in 2023 by the American Contact Dermatitis Society, with numerous studies indicating allergenicity to Lanolin and Lanolin Alcohol in patch tests. Lanolin holds FDA approval for various applications, including as a food additive and as both an active and inactive ingredient in certain OTC drug products.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Moderate

Our Assessment

Verdict

Questionable

While Isobutylated Lanolin Oil offers significant emollient and moisturizing benefits, its designation as a contact allergen for some individuals warrants careful consideration in precision skincare formulations.

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