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IODINE TRICHLORIDE.

Avoid CAS 865-44-1 / ORAL CARE

Iodine trichloride is a powerful inorganic compound, primarily utilized as a strong oxidizing, chlorinating, and iodinating agent in laboratory settings and organic synthesis. Its highly corrosive nature means it readily reacts with water, forming hydrochloric acid and elemental iodine.

Science

As a potent oxidizing agent, iodine trichloride aggressively reacts with organic compounds. Upon contact with water or moisture, it rapidly hydrolyzes, generating strong acids like hydrochloric acid and elemental iodine. This chemical interaction results in severe tissue damage, making it detrimental for direct skin application.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Iodine trichloride is explicitly contraindicated for direct skin contact in any product due to its severe corrosive properties. Therefore, its inclusion in cosmetic formulations is not considered, and 'dusting' is an irrelevant concept for this compound.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

This compound is highly sensitive to moisture and water, undergoing hydrolysis upon exposure. It also begins to decompose at temperatures above 77°C, and light exposure can cause it to redden due to the formation of elemental iodine. For optimal stability, it should be stored in cool, dry, and well-ventilated conditions, ideally at or below 20°C.

Conflicts

  • strong oxidizing agents
  • reducing agents
  • sodium
  • aluminum
  • phosphorus
  • phosphorus trichloride
  • organic matter
  • alkalis
  • metals
  • water/moist air

Safety

CIR Status
Not reviewed
Sensitization risk High

Iodine trichloride is extremely corrosive, causing severe burns to skin and eyes, and can also irritate the respiratory system. Safety Data Sheets explicitly warn against its use in products intended for direct skin contact. While the IARC has not classified it as a carcinogen at concentrations equal to or greater than 0.1%, its inherent corrosivity makes it unsuitable and dangerous for cosmetic application.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to its extreme corrosivity, severe risk of skin burns, and explicit warnings against direct skin contact, iodine trichloride must be avoided in all skincare formulations.


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