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Moumoujus

HYSSOPUS OFFICINALIS HERB OIL.

Valuable CAS 84603-66-7 / PERFUMING

Hyssopus Officinalis Herb Oil is a potent essential oil distinguished by its broad-spectrum antimicrobial activity against bacteria, yeasts, and fungi. It further offers anti-inflammatory, astringent, and antioxidant benefits, contributing to clarified, conditioned, and soothed skin while aiding in moisture retention.

Summary

Antimicrobial Anti-inflammatory Astringent Antioxidant Skin conditioning Antiseptic

Science

Mechanism of Action

This herb oil operates through multiple mechanisms to benefit the skin. Its robust antimicrobial properties inhibit the reproduction and combat various bacteria (e.g., *Escherichia coli*, *Listeria monocytogenes*) and fungi (e.g., *Candida* species, *Aspergillus niger*). It exerts anti-inflammatory effects that can alleviate skin redness and swelling. Additionally, the oil possesses mild astringent qualities to tighten and tone the skin, alongside antioxidant capabilities that defend against free radical damage. It also facilitates the shedding of dead skin cells for improved texture and aids in balancing sebum production and enhancing skin hydration.

Research

Clinical Evidence

Medium confidence
Effective range 0.15–1.5%
Optimal

1.5%

Key findings

  1. 01 Demonstrated Minimal Inhibitory Concentration (MIC) against *Candida krusei*, *Candida albicans*, and *Candida tropicalis* between 0.15-0.3% in a liquid medium.
  2. 02 Exhibited broad antimycotic activity against 10 yeast and fungi, including *C. albicans*, within concentrations of 15.625-250 µL/mL.
  3. 03 Achieved complete growth inhibition of *Aspergillus niger* at concentrations of 0.5-1.5% using an agar diffusion method.
  4. 04 Showed antibacterial efficacy with MICs of 156.25 µg/mL for *Escherichia coli* and 312.5 µg/mL for *Listeria monocytogenes*.
  5. 05 Confirmed bactericidal activity (MBC) at 312.5 µg/mL for *Escherichia coli* and 625 µg/mL for *Listeria monocytogenes*.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The ingredient's balanced chemical composition, including Pinocamphone, Limonene, and Isopinocamphone, contributes to its stability and sustained effectiveness across various applications.

Conflicts

  • High concentrations or inadequate dilution can lead to skin irritation or sensitization.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1.5%
Pregnancy
Caution
Sensitization risk Moderate

Hyssopus Officinalis Herb Oil has not undergone review by the FDA for safety or effectiveness as a drug. Given its nature as a highly concentrated essential oil, strict adherence to dilution guidelines and safe use concentrations is imperative for cosmetic formulation to mitigate irritation or sensitization risk. Historically, neurotoxicity related to terpene ketones like pinocamphone has been observed with oral consumption of hyssop oils. It is explicitly not recommended for use during pregnancy and lactation due to documented potential emmenagogue and abortifacient effects. The oil naturally contains Methyl Eugenol, with a maximum permissible concentration of 0.2% as per EU Council Cosmetic Directive 76/768/EEC Annex III.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Hyssopus Officinalis Herb Oil is a valuable ingredient for targeted skincare due to its potent antimicrobial and anti-inflammatory properties, provided it is precisely formulated within strict concentration guidelines to mitigate its moderate irritancy and specific safety concerns.

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