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HYDROXYUNDECANOIC ACID.

Insufficient Data CAS 6336-28-3 / SKIN CONDITIONING

Hydroxyundecanoic acid is a hydroxy fatty acid structurally related to the Alpha Hydroxy Acid (AHA) family. While direct specific research on its skin benefits is limited, it is hypothesized to share some exfoliating and skin renewal properties with AHAs.

Exfoliant (potential) Skin Conditioning (potential) Anti-aging (potential) Hydrating (potential)

Science

As a hydroxy fatty acid with structural similarities to Alpha Hydroxy Acids, Hydroxyundecanoic Acid is theorized to function through mechanisms characteristic of AHAs. These typically involve the chelation of calcium ions within the epidermal layer, which subsequently disrupts cellular adhesions. This process facilitates the shedding of dead skin cells, thereby promoting cellular turnover and supporting the growth of new cells. General AHA mechanisms also include the stimulation of collagen synthesis, enhancement of the skin barrier, improved hydration, and potential anti-inflammatory and depigmenting effects; however, these are extrapolations based on the broader AHA class, not direct studies on this specific molecule.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

No specific optimal pH range for stability in cosmetic formulations was identified. Its pKa is 4.78 ± 0.10, indicating its acidic nature. As a general principle for Alpha Hydroxy Acids, exfoliant efficacy is often highest at a pH below 4, while optimal skin pH for topical products typically ranges from 4 to 6.

Conflicts

  • Alkaline excipients
  • Materials sensitive to acidic conditions

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed Hydroxyundecanoic Acid. Global Harmonized System (GHS) hazard statements for 11-Hydroxyundecanoic acid indicate it 'Causes skin irritation' (H315), 'Causes serious eye irritation' (H319), and 'May cause respiratory irritation' (H335).


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Moderate

Our Assessment

Insufficient Data

While Hydroxyundecanoic Acid is structurally related to AHAs and may theoretically offer similar benefits such as exfoliation and skin conditioning, the absence of specific clinical studies, a CIR safety review, and GHS classifications indicating potential irritation mean its efficacy and safety in precision skincare are currently not well-established.


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