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Moumoujus

HYDROXYLATED LANOLIN.

Valuable CAS 68424-66-8 / ANTISTATIC, BINDING, FILM FORMING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

Hydroxylated Lanolin is a highly versatile derivative of lanolin, engineered to enhance its water-loving properties, making it more amphoteric. It serves as a potent emulsifier, a film-forming agent, and an effective emollient, delivering significant hydration and protection to the skin.

Summary

Antistatic Binding Film Forming Skin Conditioning Skin Conditioning - Emollient Surfactant - Emulsifying

Science

Mechanism of Action

This ingredient functions by modifying interfacial tension, allowing for the stable emulsification of immiscible liquids like oil and water within formulations. On the skin, it creates a continuous, protective film that significantly reduces transepidermal water loss, thus softening and conditioning the skin. The hydroxylation process increases its hydrophilic character, differentiating it from basic lanolin.

Research

Clinical Evidence

Medium confidence
Effective range 0.5–17.5%
Optimal

N/A

Key findings

  1. 01 No visible skin changes were observed in 53 human subjects when exposed to concentrations up to 100%.
  2. 02 Demonstrated non-comedogenic properties at a 6% concentration when tested on rabbit ears.
  3. 03 No evidence of phototoxicity or photosensitization was found in human subjects using product formulations containing 0.5% Hydroxylated Lanolin.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Hydroxylated Lanolin exhibits a melting range between 39°C and 46°C.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
17.5%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has consistently reaffirmed Hydroxylated Lanolin's safety for topical application in cosmetics, most recently in a March 2024 draft report. Its maximum reported use in leave-on products is 17.5%. The U.S. FDA broadly permits Lanolin in OTC drugs and as a food additive. Sensitivity concerns historically linked to lanolin are primarily associated with Lanolin Alcohols, not Hydroxylated Lanolin.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Medium

Our Assessment

Verdict

Valuable

Hydroxylated Lanolin is a valuable multifunctional ingredient, offering significant emollient, film-forming, and emulsifying benefits with a well-established safety profile, particularly beneficial for dry and sensitive skin types.

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