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Moumoujus

HYDROXYETHYL IMIDAZOLIDINONE.

Questionable CAS 3699-54-5 / HUMECTANT

HYDROXYETHYL IMIDAZOLIDINONE is a humectant ingredient recognized for its potential to enhance skin barrier function and elasticity. It achieves this by acting as a dual inhibitor on key enzymes involved in skin integrity and hydration. However, its raw material is associated with irritation warnings, necessitating careful consideration.

Summary

Humectant

Science

Mechanism of Action

HYDROXYETHYL IMIDAZOLIDINONE (HEI) functions as a dual enzymatic inhibitor, targeting both heparanase and Matrix Metalloproteinase-9 (MMP-9). Inhibition of heparanase may support basement membrane integrity, while MMP-9 inhibition can contribute to improved skin elasticity and a fortified epidermal barrier.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Topical application improved epidermal barrier function by increasing water content and decreasing transepidermal water loss in daily sun-exposed facial skin.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Exhibits excellent thermal stability, remaining stable at temperatures exceeding 200°C.

Conflicts

  • strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

GHS classifications for the raw material indicate potential for irritation, specifically 'Causes skin irritation' (H315, reported in 56.2% of cases) and 'Causes serious eye irritation' (H319, reported in 56.2% of cases).

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While demonstrating potential benefits for skin barrier and elasticity, the ingredient's 'not reviewed' CIR status and documented raw material irritation warnings necessitate a cautious approach in formulation and use.

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