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HYDROXYETHYL ETHYLCELLULOSE.

Valuable CAS 9004-58-4 / BINDING, EMULSION STABILISING, FILM FORMING, SURFACTANT - EMULSIFYING, VISCOSITY CONTROLLING

Hydroxyethyl Ethylcellulose is a versatile, nonionic cellulose derivative primarily valued in skincare for its rheology-modifying and film-forming capabilities. It effectively enhances product texture and stability while creating a breathable, hydrophilic film on the skin to boost moisture retention without occlusion.

Viscosity controlling Emulsion stabilising Film-forming Moisture retention Ingredient release control

Science

This ingredient functions by forming a non-occlusive, hydrophilic film on the skin's surface, which helps to maintain moisture levels and reduce transepidermal water loss, promoting a hydrated feel. In formulations, its molecular chains construct a three-dimensional network within aqueous solutions, significantly increasing viscosity and controlling rheological properties to ensure consistent product texture. Furthermore, it aids in stabilizing emulsion interfaces and can modulate the controlled release of other active ingredients.


Research

High confidence
Effective range 0.1–5%
Optimal

Typically used at 0.5%-2% for lotions and creams (0.5%-1% for lightweight, 1%-2% for rich), and 0.4%-1.5% for masks, to optimize texture and moisturizing benefits.

Key findings

  1. 01 Clinical evaluations at concentrations up to 100% indicate that Hydroxyethyl Ethylcellulose is non-irritating to mildly irritating, non-sensitizing, and non-photosensitizing to the skin.

Transparency

Not commonly dusted

Information regarding 'dusting' specific to Hydroxyethyl Ethylcellulose is not available in the provided research data.


The Formula

Solubility
Water
Optimal pH 5.5 – 7
0 7 14

Stability

Optimal stability and thickening efficiency are observed within a pH range of 5.5–7.0, consistent with the skin's natural acidic mantle. While its nonionic nature provides stable thickening effects across a broader pH range of 3-11, conditions below pH 5.5 may hinder complete dissolution, and above pH 7.0 may reduce thickening efficacy. Raw material storage requires a sealed container in a dry, cool, well-ventilated environment, protected from moisture, temperatures exceeding 40°C, and direct sunlight to prevent caking and degradation.

Conflicts

  • Direct contact with high-valent metal ions (e.g., iron, aluminum) and strong oxidizing agents can degrade the polymer and reduce viscosity.
  • High concentrations of strongly alkaline surfactants should be avoided; mild surfactants like alkyl glucosides or sodium lauryl sulfate are preferred.
  • When formulated with retinoids or strong acidic ingredients (e.g., AHAs, salicylic acid), its concentration should be reduced (typically ≤0.5%), and compatibility testing is essential to prevent potential skin irritation.
  • Formulations containing natural extracts or protein-based ingredients require the use of dual preservatives to effectively inhibit microbial growth.

Safety

CIR Status
Safe as used
Max tested
100%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has determined Hydroxyethyl Ethylcellulose to be safe for use in cosmetics. Extensive ocular and dermal irritation studies, even at concentrations up to 100%, showed it to be minimally irritating to eyes and non-irritating to slightly irritating to the skin. It is recognized as a safe and effective ingredient with a low likelihood of causing adverse reactions, supported by decades of safe use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Hydroxyethyl Ethylcellulose is a valuable, well-tolerated ingredient that significantly contributes to product elegance and efficacy by stabilizing formulations and providing effective, breathable skin hydration across all skin types.


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