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HYDROXYETHYL ACRYLAMIDE.

Avoid CAS 7646-67-5 / BINDING

Hydroxyethyl Acrylamide (HEAA) is a hydrophilic monomer primarily utilized as a building block in the synthesis of various polymers, including hydrogels and coatings. While essential for modifying the material properties of these synthesized compounds, it does not possess established direct cosmetic benefits for the skin as a standalone ingredient.

Science

As a monomer, Hydroxyethyl Acrylamide enhances water solubility and hydrogen bonding interactions when incorporated into polymer structures, thereby influencing properties such as swelling and biocompatibility. However, current scientific literature does not define a direct mechanism of action or any specific cosmetic benefits for this ingredient when applied to the skin in its standalone form.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Hydroxyethyl Acrylamide is a monomer without established direct cosmetic benefits or a defined mechanism of action on the skin in its standalone form. Consequently, the concept of 'dusting' for an active cosmetic effect does not apply.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

N-Hydroxyethyl acrylamide is an amide monomer exhibiting superior resistance to hydrolysis compared to ester monomers. It is typically supplied stabilized with polymerization inhibitors, such as 1,000 ppm monomethyl ether hydroquinone (MEHQ), to prevent unwanted photo-polymerization. The pH of its solution is approximately 7.

Conflicts

  • Forms explosive mixtures with air on intense heating.

Safety

CIR Status
Safe with restrictions
Max tested
5%
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that acrylamide/acrylate copolymers, which may include Hydroxyethyl Acrylamide as a monomer, are safe in cosmetics provided the residual acrylamide monomer concentration does not exceed 5 ppm. However, the monomer itself (N-Hydroxyethyl acrylamide) is classified with warnings indicating it may cause an allergic skin reaction, skin irritation, and serious eye irritation. It is also identified as a specific target organ toxicant with prolonged or repeated exposure. The Scientific Committee on Cosmetic Products and Non-Food Products (SCCNFP) in the EU established even stricter limits for residual acrylamide: 0.1 ppm for leave-on products and 0.5 ppm for other cosmetic products.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

As a monomer, Hydroxyethyl Acrylamide presents significant safety concerns including potential irritation and sensitization, and lacks established direct cosmetic benefits, requiring strict regulatory limits on residual concentrations in formulations.


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