Science
Mechanism of Action
This ingredient operates as a Norrish Type I photoinitiator. Upon exposure to UV light, it undergoes an α-cleavage, a homolytic bond breaking between the carbonyl group and an adjacent carbon. This reaction yields highly reactive free radical fragments which then initiate the polymerization of monomers and oligomers, a process critical for hardening UV-curable materials, not for direct biological activity on the skin.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
This ingredient is not commonly used as a standalone active in skincare for direct skin benefits; therefore, 'dusting' considerations are not applicable.
The Formula
Formulation
Stability
The substance maintains stability under recommended temperatures and pressures; however, specific pH range for optimal stability has not been determined.
Conflicts
- strong oxidizing agents
Safety
Safety Profile
No specific CIR, FDA, or SCCS review was identified. This compound has been reclassified under EU REACH regulations as Reproductive Toxicity Category 1B, indicating it is considered a reprotoxic substance. The Globally Harmonized System (GHS) classification suggests it may cause skin and serious eye irritation, and potentially respiratory irritation. An initial threshold screening level (ITSL) of 0.1 μg/m3 based on an annual averaging time has been established for airborne exposure.
Your Skin
Skin Compatibility
Our Assessment
Verdict
HYDROXYCYCLOHEXYL PHENYL KETONE is primarily an industrial photoinitiator, poses significant safety concerns including reprotoxicity and potential irritation, and offers no proven direct benefits for skin health.
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References
Sources