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HYDROXYBUTYL METHACRYLATE.

Avoid CAS 13159-51-8 / BINDING

Hydroxybutyl Methacrylate is a reactive monomer primarily used in polymerization processes to form various polymers and copolymers, often enhancing material properties through crosslinking. Despite its utility in industrial and biomedical sectors, its significant potential for skin irritation and sensitization necessitates strict avoidance of direct dermal contact in cosmetic applications.

Monomer Polymerizing Agent

Science

As a reactive methacrylate monomer, Hydroxybutyl Methacrylate engages in free radical polymerization to construct durable polymer networks. While its hydroxyl group facilitates robust hydrogen bonding and crosslinking for material strength, it offers no beneficial mechanism for skin. Instead, direct dermal exposure is associated with irritation and allergic sensitization.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

This monomer maintains stability under standard conditions but is prone to hydrolysis in the presence of strong acids or bases. To prevent premature polymerization, it is typically stabilized with inhibitors, such as monomethyl ether hydroquinone. Optimal storage for related methacrylates recommends maintaining air exposure with a stabilizer at temperatures not exceeding 35°C.

Conflicts

  • Substances initiating free radical polymerization
  • Strong acids
  • Strong bases
  • Direct skin contact

Safety

CIR Status
Safe with restrictions
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel deemed Hydroxybutyl Methacrylate safe for use in nail enhancement products, provided that direct skin contact is strictly prevented due to its pronounced sensitizing potential. All products containing this ingredient must include explicit warnings to avoid dermal exposure. Although no specific SCCS opinion exists for Hydroxybutyl Methacrylate, related methacrylates are categorized as sensitizing and irritant, frequently restricted to professional nail plate application. Global Harmonized System (GHS) classification further indicates it causes skin and serious eye irritation, along with potential allergic skin reactions.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to its high potential for causing skin irritation and allergic sensitization upon direct dermal contact, Hydroxybutyl Methacrylate is explicitly unsuitable for inclusion in direct skin contact skincare formulations.


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