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HYDROXY TETRAMETHYLPIPERIDINE OXIDE.

Valuable CAS 2226-96-2 / ANTIOXIDANT

Hydroxy Tetramethylpiperidine Oxide is a highly effective antioxidant and radical scavenger, specifically formulated to protect skin from the detrimental effects of oxidative stress. It contributes to cellular integrity by neutralizing reactive oxygen species, promoting a healthier and more resilient complexion.

Antioxidant Radical Scavenger Skin Protection

Science

This compound operates by actively disarming various reactive oxygen species and free radicals, thereby mitigating cellular oxidative damage. Its mechanism involves catalyzing the disproportionation of superoxide, facilitating the metabolism of hydrogen peroxide, and inhibiting the damaging Fenton reaction.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Hydroxy Tetramethylpiperidine Oxide enhances the thermal and oxidative stability of formulations. It is readily soluble in both water and organic solvents such as ethanol and benzene. Due to its hygroscopic nature, it must be stored in a closed, dry environment away from high temperatures to maintain efficacy and prevent moisture absorption.

Conflicts

  • oxidizing agents

Safety

CIR Status
Safe as used
Max tested
0.019%
Sensitization risk Low

The CIR Expert Panel concluded Hydroxy Tetramethylpiperidine Oxide is safe for cosmetic use at current concentrations, with a maximum recommended concentration of 0.019%. While GHS hazard statements for the raw chemical indicate potential for skin and serious eye irritation, as well as harm if swallowed, dermal irritation was not observed in rats at 0.5g. However, undiluted application of 0.1g caused irreversible eye damage in rabbits.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Hydroxy Tetramethylpiperidine Oxide is a valuable antioxidant and radical scavenger that protects skin from oxidative stress, deemed safe for use in cosmetics at concentrations up to 0.019%.


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