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Moumoujus

HYDROLYZED PUNICA GRANATUM MESOCARP EXTRACT.

Valuable / HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Hydrolyzed Punica Granatum Mesocarp Extract is a nutrient-rich derivative from the pomegranate's inner peel, celebrated for its potent antioxidant and anti-inflammatory properties. This botanical ingredient is engineered to support skin health by mitigating environmental stressors and enhancing cellular vitality. It actively works to diminish visible signs of aging, promote an even skin tone, and maintain optimal hydration.

Summary

Antioxidant Anti-inflammatory Collagen Booster Skin Brightening Sebum Regulator Humectant Skin Conditioning Emollient

Science

Mechanism of Action

Operating at a cellular level, Hydrolyzed Punica Granatum Mesocarp Extract delivers a complex blend of polyphenols, ellagic acid, punicalagins, and Vitamin C, acting as powerful scavengers against free radicals to prevent oxidative damage. Its anti-inflammatory action helps calm and reduce skin irritation across various conditions. The extract supports dermal structural integrity by stimulating collagen synthesis, which improves elasticity and reduces the appearance of fine lines. Furthermore, its natural humectant properties contribute to enhanced skin hydration. Ellagic acid selectively inhibits tyrosinase activity by chelating copper, thereby reducing melanin production for a brighter, more uniform complexion. Specific hydrolysable tannins may also assist in moderating sebum secretion, while polyphenols can offer a degree of protection against UV-induced damage by inhibiting NF-kappa B pathways.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Significantly reduced crow's feet wrinkles, tactile roughness, and forehead fine lines. Improved skin radiance, moisturization, elasticity, and firmness. A 3% reduction in Tyrosinase biomarker levels was also observed.
  2. 02 No dermal irritation observed with daily application.
  3. 03 Demonstrated antimicrobial efficacy against common oral pathogens.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Punica Granatum Extract typically exhibits an acidic pH of 3.0-4.0. Some pericarp extracts may present solubilization challenges, often requiring specific cosmetic solvents like an 80:20 v/v Gly:H2O mixture for stability over three months at 5°C. Alcoholic extracts show solubility in various aqueous solutions (e.g., 0.1 N HCl, 0.1 N NaOH, 0.9% NaCl, phosphate buffers pH 4, 7 & 10) and some organic solvents like 95% ethanol.

Conflicts

  • DMSO (dimethyl sulfoxide)

Safety

Safety Profile

CIR Status
Safe as used
Max tested
10%
Sensitization risk Low

The CIR Expert Panel concluded *Punica granatum*-derived ingredients, including those containing mesocarp, are safe under current cosmetic uses and concentrations. An in vitro human epidermal model predicted non-irritation for a tradename mixture containing 10% Punica Granatum Pericarp Extract. US FDA generally recognizes *Punica granatum Linnaeus* extracts as safe (GRAS) for food applications. Human sensitization tests for 0.1% Punica Granatum Fruit Extract and 0.5% solids Punica Granatum Pericarp Extract were negative.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

This extract offers broad benefits for skin health, leveraging potent antioxidant and anti-inflammatory properties, with a robust safety profile for diverse skin types.

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