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HYDROLYZED CORN/SOY/WHEAT PROTEIN THIOGLYCOLAMIDE/THIOPROPIONAMIDE.

Insufficient Data / HAIR CONDITIONING, SKIN CONDITIONING

This advanced ingredient combines hydrolyzed proteins from corn, soy, and wheat, chemically modified with thioglycolamide and thiopropionamide. It functions as a skin and hair conditioning agent, helping to maintain skin health and impart moisturizing, film-forming properties.

Summary

Hair Conditioning Skin Conditioning

Science

Mechanism of Action

The hydrolyzed protein components within this ingredient create a moisturizing and protective film on the skin's surface. This action enhances skin conditioning, contributing to a smoother texture and improved overall skin appearance.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

Hydrolyzed proteins generally exhibit enhanced solubility and thermal stability. For the corn and soy protein components, solubility typically increases within a pH range of 6.0 to 8.0 and with elevated temperatures (30-70°C). Minimum solubility often occurs around the isoelectric pH (e.g., pH 5.0). Specific stability data for the thioglycolamide/thiopropionamide modified complex is not explicitly available, though optimal hydrolysis for similar protein mixtures is often noted between pH 7.0 and 8.0.

Conflicts

  • Should not be used on compromised skin, or in products with potential for contact with mucous membranes or incidental inhalation. This caution is particularly important if the hydrolyzed wheat protein component contains peptide lengths exceeding 30 amino acids (approximately 3500 Da).

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has evaluated hydrolyzed corn protein and hydrolyzed soy protein individually, concluding they are safe for cosmetic application. Hydrolyzed wheat protein and hydrolyzed wheat gluten were deemed safe for cosmetic use under strict conditions: peptides must be restricted to a weight-average molecular weight of 3500 Da or less (equivalent to no more than 30 amino acids). Additionally, these wheat protein ingredients are not advised for use on damaged skin, in products contacting mucous membranes, or those that may be incidentally inhaled. A direct CIR or SCCS review for the combined 'HYDROLYZED CORN/SOY/WHEAT PROTEIN THIOGLYCOLAMIDE/THIOPROPIONAMIDE' ingredient is not available. While individual hydrolyzed proteins are considered GRAS for food use by the FDA, this specific combined ingredient lacks a dedicated cosmetic status.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While individual hydrolyzed proteins offer known benefits, the specific combined ingredient lacks comprehensive safety and efficacy data, particularly regarding its thioglycolamide/thiopropionamide modification, warranting cautious consideration and further research.

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