Science
Mechanism of Action
As a propellant, HFC-227ea facilitates the expulsion of product from an aerosol container through rapid vaporization from its liquid to gaseous state. While its gaseous form is considered non-irritating upon skin contact, direct exposure to its liquid form can cause a significant cooling effect due to rapid vaporization, potentially leading to frostbite.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
As a gaseous propellant, Hydrofluorocarbon 227ea is not relevant for dusting analysis typically associated with powdered ingredients.
The Formula
Formulation
Stability
Hydrofluorocarbon 227ea maintains thermal and chemical stability under normal temperatures and storage conditions. However, heating can lead to decomposition, releasing hazardous byproducts such as hydrogen fluoride and carbon oxides. Formulators should also be aware that certain mixtures with chlorine may become flammable or reactive.
Conflicts
- Decomposes on heating (releases hydrogen fluoride, carbon oxides)
- Mixtures with chlorine (potentially flammable/reactive)
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not specifically evaluated Hydrofluorocarbon 227ea. The U.S. FDA has identified HFC-227ea as a PFAS, noting significant data gaps that prevent a conclusive safety determination, although it is not currently prohibited in cosmetic products. A critical safety concern is the risk of frostbite from direct dermal contact with the liquid form.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hydrofluorocarbon 227ea effectively functions as a propellant; however, its classification as a PFAS, combined with notable data gaps regarding its safety and the risk of frostbite from liquid contact, positions it as a questionable ingredient for precision skincare formulations.
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