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HYDROFLUOROCARBON 152A.

Optional CAS 75-37-6 / PROPELLANT

Hydrofluorocarbon 152A is an inert gaseous compound primarily utilized as a propellant in precision skincare formulations. It facilitates product dispersion through rapid volatilization upon application, demonstrating minimal direct interaction with or metabolism on the skin.

propellant

Science

Functioning as a propellant, Hydrofluorocarbon 152A enables the precise and controlled dispensing of product formulations. Its largely inert nature ensures it quickly evaporates after application, effectively delivering active ingredients without contributing direct biological activity or significant cutaneous metabolism.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

This substance is a flammable gas, requiring strict avoidance of open flames and elevated temperatures. Its decomposition can yield hazardous byproducts, including hydrofluoric acid (HF) and potentially carbonyl fluoride (COF2).

Conflicts

  • alkali metals
  • alkaline earth metals
  • powdered metals (e.g., Al, Zn, Be)

Safety

CIR Status
Safe as used
Max tested
45%
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded Hydrofluorocarbon 152A is safe for use in cosmetics at present concentrations and practices, with reported general dermal contact uses up to 45%. Extensive inhalation safety studies affirm its use in cosmetic spray products does not pose adverse health effects when utilized as directed. Due to its gaseous state, dermal irritation and sensitization studies are not technically feasible; however, an eye irritation test (BCOP assay) with an 80% concentration showed no irritation. It is important to note that the European Union has implemented regulations restricting fluorinated gases in personal care products for environmental protection, which is separate from human safety assessments. The FDA does not mandate pre-market approval for cosmetic ingredients, and manufacturers are responsible for ensuring product safety. Hydrofluorocarbon 152A is not classified as a PFAS (per- and polyfluoroalkyl substance) by the FDA.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Optional

Hydrofluorocarbon 152A is a safe and effective propellant, crucial for the precise delivery of certain cosmetic formulations, though it offers no direct skin benefits.


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