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Moumoujus

HYDROFLUOROCARBON 134A.

Avoid CAS 811-97-2 / PROPELLANT

Hydrofluorocarbon 134A (HFC-134a) is an organic compound primarily utilized as a propellant in various aerosol formulations, enabling the precise dispensing of product. It also demonstrates efficacy as a cryogen for rapid skin cooling during specific medical procedures.

Summary

Propellant Cryogenic Agent

Science

Mechanism of Action

Functions predominantly as a propellant by creating pressure within aerosol containers, facilitating product expulsion. As a cryogen, its mechanism involves rapid evaporative cooling upon contact with the skin surface, specifically employed to mitigate thermal injury during procedures such as laser treatments.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Effectively used as a cryogen spray cooling (CSC) agent to prevent thermal injury to the epidermis during laser treatments, particularly in darker skin types, by increasing the threshold for irreversible thermal damage.

Transparency

Dusting Analysis

Not commonly dusted

Not applicable; this ingredient functions as a propellant or cryogen rather than a solid ingredient prone to dusting.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Exhibiting general stability, tests indicate long-term stability even when exposed to temperatures up to 175°C for 14 days in the presence of metals and refrigeration lubricants.

Conflicts

  • Active metals
  • Strong oxidizing agents
  • Freshly abraded aluminum surfaces (potential exothermic reaction)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel has not evaluated Hydrofluorocarbon 134A for cosmetic use. Classified by EWG as a hydrofluorocarbon (HFC) and a per- and polyfluoroalkyl substance (PFAS), it raises significant concerns regarding potential for cancer, allergies, immunotoxicity, developmental and reproductive toxicity, endocrine disruption, persistence, bioaccumulation, and non-reproductive organ system toxicity. While possessing very low acute toxicity, high-concentration inhalation can induce cardiac arrhythmia, unconsciousness, or be fatal. Direct liquid contact may result in frostbite. It is, however, approved by the FDA as a propellant for specific medical applications, such as metered-dose inhalers.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Despite its utility as a propellant and medical cryogen, the classification as a PFAS with broad high safety concerns from EWG and absence of CIR review render this ingredient unsuitable for Moumoujus skincare formulations.

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