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Moumoujus

HYDROCHLOROFLUOROCARBON 22.

Avoid CAS 75-45-6 / PROPELLANT

Hydrochlorofluorocarbon 22 (HCFC-22), also known as chlorodifluoromethane, is an industrial chemical explicitly not recognized or permitted as a cosmetic ingredient. Its primary association is with ozone depletion, leading to its global phase-out under environmental protocols. Direct dermal exposure poses significant risks, including severe irritation and frostbite.

Summary

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

This substance is not recognized as a cosmetic ingredient and is therefore not relevant for dusting analysis in skincare formulations.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Conflicts

  • alkalis
  • alkaline earth metals (e.g., powdered aluminum, sodium, potassium, zinc)

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk High

Hydrochlorofluorocarbon 22 (HCFC-22) is not permitted for use in cosmetic products. The U.S. FDA specifically prohibits the use of chlorofluorocarbon propellants in cosmetic aerosol products. Furthermore, HCFC-22 is classified as an ozone-depleting substance, leading to its global phase-out under the Montreal Protocol due to significant environmental impact. Direct contact with its liquid form can induce severe skin and eye irritation, alongside frostbite.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Hydrochlorofluorocarbon 22 is strictly prohibited in skincare due to severe environmental impact and direct contact hazards, rendering it unsuitable and illegal for cosmetic formulation.

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